A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – TELEMEDICINE

• Chunyu Yisheng, a smartphone marketplace app that lets users remotely consult with physicians, completed a $183M funding round. Link
• Teladoc, a provider of telehealth services, secures $50M in Debt financing from Silicon Valley Bank. Link
• MindCare Solutions, a provider of behavioral health care services through a telemedicine platform, raised $19M in Series A round of funding. Link
• Aligned Telehealth, a telemedicine and healthcare management company, closed a Series A equity funding of $12M. Link
• Avizia, a telehealth solution provider offering an end-to-end platform, raised $11M in Series A round of funding led by Blue Heron Capital and joined by Lavrock Ventures, NextGen Venture Partners, Middleland Capital, Waterline Capital, and Blu Ventures. Link
• 39 Hospital, a secondary diagnosis and consultation platform for severe problems via telemedicine application, raised $7.5M in Series A round of funding led by IDG Ventures. Link
• SnapMD, a cloud-based patient-to-provider telemedicine platform, raised $1.5M in Series A round. Link
• YourDost, an online counselling and psychological support platform, raised $1.2M in Series A round of funding led by SAIF Partners. Link
• SeeDoc, a mobile-based telemedicine platform which provides patients access to a network of doctors, raised $1M in its pre-Series A round of funding led by early stage venture fund YourNest, Sunil Goyal, founder and CEO, YourNest Angel Fund. Link
• TeleHealth 365, a cloud-based video conferencing solution for healthcare providers and their patients, received an angel round of funding from a private investor. Link
• HelathiestYou, a telehealth consumer engagement technology platform for the small to mid-sized employer market, got acquired by Teladoc for $125M. Link

SOME INTERESTING STARTUPS FOUND

Coordination Centric (2015, McAllen) – Monitor chronic conditions like Diabetes, Hypertension, Chronic Heart Failure & COPD and relays this information to their health care providers. Vitals are measured using at home monitoring devices and the results are sent to the health care coordinator via a cellular gateway.

LEADER BOARD – TELEMEDICINE

Tele-Consultation
Teladoc (2002, Dallas, IPO) – Telemedicine provider offering web and mobile based video consultation. Backed by Cardinal Partners, HLM Venture Partners, Trident Capital, New Capital Partners, Jafco Ventures, Kleiner Perkins Caufield & Byers, Greenspring Associates, BNY Mellon, Questmark Partners, FLAG Capital Management. Went public in July 2015.
Specialists On Call (2004, Reston, $132M) – Telemedicine services for Tele-Neurology, Tele-Psychiatry and Tele-Intensivist. Backed by Warburg Pincus.
American Well (2006, Boston, $123M) – Telehealth platform that connects users with doctors. Backed by Inventure Partners.
Doctor On Demand (2012, SF, $87M) – Telemedicine services based on a pay-per-use model. Backed by Venrock, Shasta Ventures, Qualcomm Ventures.
MDLIVE (2009, Sunrise, $74M) – Online and on-demand telemedicine services. Backed by Bedford Funding, Heritage Group, Sutter Health, Kanye Capital.

Tele-Monitoring
iRhythm Technologies (2006, SF, $95M) Remote cardiac rhythm monitoring device. Backed by Mohr Davidow Ventures.
Watermark Medical (2008, Boca Raton, $53M) Home sleep testing solutions to determine presence and severity of obstructive sleep apnea. Merged with SleepMed. Backed by Ballast Point Ventures.
MD Revolution (2011, San Diego, $34M) Platform for healthcare providers to predict and prevent chronic disease via behaviour change. Backed by Jump Capital.
Healthsense (2001, Mendota, $33M) Remote monitoring, emergency calls and wellness management solutions. Backed by Radius Ventures, Merck & Co., Mansa Capital, Merck Global Health Innovation Fund.

Tele-Rehabilitation
Pursuant Health (2007, Atlanta, $29M) Interactive healthcare platforms and kiosks. Backed by WellPoint, Novartis, Dell, Coinstar.

Tech Enablers
InTouch Health (2002, Santa Barbara, $64M) Proprietary communications and mobile robotic platform. Backed by Acacia VP, iRobot, Beringea.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates visit Telemedicine feeds

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – MEDICAL DEVICES

• Medpace, a contract research organization, released the pricing for its initial public offering which will bring in between $140M and $161M. Link
• CVRx, a developer of implant to treat heart failure, raised $93M in a Series G round led by Johnson & Johnson’s venture arm and $20M from a new debt facility. Link
• VytronUS, a developer of technologies for the treatment of cardiac arrhythmia, raised $49M is a Series C round from Apple Tree Partners, NEA, BioStar Ventures, and Windham Ventures. Link
  
• Direct Flow Medical, a developer of transcatheter aortic valve, raised $27M in a Series D round from 11 anonymous investors. Link
  
• Torax Medical, a developer of products to restore human sphincter function, raised $25M in a Series E round led by Johnson & Johnson’s venture arm. Link
• Osprey Medical, a developer of technology to reduce contrast dye exposure, raised $21M from institutional investors. Link
• Precision Ocular, a developer of drug delivery technology for ophthalmology, completes a £15.5M Series A funding round from Imperial Innovations, Consort Medical, NeoMed, V-Bio Ventures and Hovione Scientia. Link
  
• Ornim, a developer of noninvasive continuous blood-flow monitor, raised $20M in a Series C round led by LongTec HongTao China Ventures. Link
• GC Aesthetics, a developer of breast implants, raised $20M in a Series D funding round from Montreux Equity Partners, Oyster Capital and Barry’s Tea Holdings. Link
• Cambridge Medical Robotics, a developer of robotic systems for minimally invasive surgery, raised $20M in a Series A round from ABB Technology Ventures, LGT Global and Cambridge Innovation Capital. Link
• nVision Medical, a developer of microcatheter technology that allows access to the fallopian tubes, raised $12M in a Series B round led by Arboretum Ventures. Link
• Establishment Labs, a developer of breast implant technologies, raised an additional $6.8M to complete a $28M funding round from Crown Predator Holdings, JW Funds and Perceptive Advisors. Link
• Check-Cap, a developer of ingestible imaging capsule, raises $6M from an institutional investor. Link
• Mirabilis Medica, a developer of ultrasound based imaging and ablation devices to remove uterine fibroids, raises $5M in debt financing. Link
• DreaMed Diabetes, a developer of diabetes treatment and management solutions, raised $3.3M in a Series A funding round led by Norma Investments. Link
• Saranas, a developer of technology for the detection of internal bleeding during catheterization procedures, raised $1.4M is a Series A funding round. Link
• Beta Bionics, a developer of artificial pancreas, raised $1M in as equity crowdfunding round. Link
• Titan Spine, a developer of interbody fusion devices for spinal surgery, raised an Undisclosed funding from Southlake Equity Group. Link
• Zimmer Biomet has entered into the surgical robotics arena with the purchase of France’s Medtech for an estimated $132M. Link
• InSeal Medical won CE Mark approval for its InClosure vascular closure device designed to close large bore arterial punctures. Link
• Accuray won CE Mark approval for its Radixact treatment delivery platform designed for image-guided radiotherapy treatments. Link
• Relievant Medsystems won FDA 510(k) clearance for its Intracept intraosseous nerve ablation system designed for the treatment of chronic lower back pain. Link

SOME INTERESTING STARTUPS FOUND

Nuviant Medical (2014, Liege) – Develops Implantable neurostimulation systems for chronic diseases.
Aura Innovative Robotics (2015, Madrid) – Develops a diagnosing device for neurological and mental disorders.
Neurescue (2014, Copenhagen) – Develops a diagnosing device for neurological and mental disorders.

LEADER BOARD – MEDICAL DEVICES

THERAPEUTICS

Cardiovascular
TriVascular (1998, Santa Rosa, IPO) – Medical devices for endovascular aortic repair. Went public in 2014.
CVRx (2001, Minneapolis, $390M) – Implantable technology for hypertension and heart failure. Backed by DaVita Healthcare Partners, Piper Jaffray, Ysios Capital, JJDC, InterWest Partners, Silicon Valley Bank, SightLine Partners, NEA, Kearny Venture Partners, Frazier Healthcare Partners, ABS Ventures.

Orthopedics
ConforMIS (2004, Bedford, IPO) – Personalized, partial knee resurfacing implants to treat knee osteoarthritis. Went public in 2015.
Small Bone Innovations (2009, Morrisville, $171M) – Suite of orthopedic products for small bones and joints. Backed by Trevi Health Ventures, Goldman Sachs, Malaysian Life Sciences Capital Fund, NGN Capital, Viscogliosi Brothers, Axiom Ventures, Khazanah Nasional Berhad, 3i Group.

Surgery
Auris Surgical Robots (2009, San Carlos, $184M) – Robotic microsurgical systems for ophthalmic surgery. Backed by NaviMed Capital, Lux Capital, Mithril Capital Management and Highland Capital Partners.
Medrobotics (2011, Raynham, $140M) – Robotic surgical devices for minimally invasive surgery. Backed by Hercules Technology Growth Capital and Pittsburgh Life Sciences Greenhouse.

Ophthalmology
TearScience (2005, Morrisville, $151M) – Diagnosis and Treatment of Evaporative Dry Eye. Backed by Spray Venture Partners, Essex Woodlands Health Ventures, eneralcatalyst.com, HealthCare Royalty Partners, Investor Growth Capital, DeNovo Ventures and Quaker BioVentures.
Avedro (2007, Waltham, $130M) – Corneal cross-linking technology. Backed by Interwest, OrbiMed Advisors, Prism Venture Management, DeNovo Ventures, Flagship Ventures, Aperture Venture Partners, SCP Vitalife Partners, Borealis Ventures, Abingworth, Third Point, and Prism Venture.

DIAGNOSTICSPlatform Technologies
Neusoft Medical System (1998, Shenyang, $410M) – Medical imaging device and software developer. Backed by China Everbright Group AG, Goldman Sachs, Hony Capital.
Butterfly Network (2011, Guilford, $100M) – Medical imaging devices using a combination of deep learning and an ultrasonic device. Backed by Aeris Capital.

Oncology
Impedimed (1999, Carlsbad, $106M) – Bioimpedance Spectroscopy technologies. Backed by Versant Venture Management, Starfish Ventures.
Veran Medical (2005, St.Louis, $83M) – Soft tissue navigation for diagnosis of lung cancer. Backed by Prolog Ventures, Versant Ventures, River Cities Capital Funds, Advantage Capital Partners, Rex Health Ventures, 3G Capital Partners and Vectis.

Infectious Disease
Accelerate Diagnostics (2004, Tucson, IPO) – In vitro diagnostics to provide solutions for the antibiotic resistant infections. Went public in 2013.
Curetis (2007, Holzgerlingen, $85M) – Molecular diagnostics POC device for infectious diseases. Backed by Forbion, KfW Bankengruppe, HBM Partners, BioMedPartners, CD-Venture GmbH, Roche, Qiagen, Life Sciences Partners, Aeris Capital.

MONITORING Diabetes
OptiScan Biomedical (1994, Hayward, $156M) – Glucose monitoring systems for ICUs/CCUs. Backed by yet2Ventures, Mitsui, Medven, Lightstone Ventures, Oakwood Medical, Ascension Ventures, NGN Capital, Signet Healthcare Partners, Mitsui, Hercules Technology Growth Capital, Prism Venture, EGS Healthcare Capital Partners, Morgenthaler.
Senseonics (1996, Germantown, $124M) – Implantable system for continuous glucose monitoring. Backed by NEA, HealthCare Ventures, Rho Capital Partners, Anthem Capital Management, Delphi Ventures and Greenspring Associates.

Cardiovascular
CardioMEMS (2001, Atlanta, $153M, Acq.) – Wireless sensor-based implants for cardiac monitoring. Acquired by St. Jude Medical in 2014.
iRhythm Technologies (2006, SF, $95M) – Cardiac rhythm monitoring devices. Backed by Mohr Davidow Ventures, Synergy Life Science Partner, Novo A/S, Norwest Venture Partners, California HealthCare Foundation, Stanford University, Kaiser Permanente Ventures, New Leaf Venture Partners and New Leaf Ventures.

Vital Signs
EarlySense (2004, Ramat Gan, $85M) – Contact free patient monitoring solution. Backed by Noaber, Bridge Investment Fund, Samsung Venture Investment Corporation, Docor, ProSeed, Pitango VC, Israel, Mitsui & Co, JK&B Capital, Bank Hapoalim, Welch Allyn, Challenge.
Sotera Wireless (2004, San Diego, $68M) – In hospital patient monitoring device. Backed by Sanderling Ventures, Qualcomm Ventures, Intel Capital, EDB Investments, Safeguard, Delphi Ventures, Cerner Capital, West Health and Sanderling.

CLINICAL EQUIPMENT
TransMedics (1998, Andover, $264M) – Organ transplantation technology. Backed by Tudor Funds, Abrams Capital, Flagship Ventures, Kleiner Perkins, Foundation Capital, Sagamore, Hercules Technology Growth Capital, Alta Partners, Sherbrooke Capital, VantagePoint Capital Partners and i Group plc.
Caesarea Medical Electronics (1993, Caesarea, $100M) – Infusion and syringe pump systems and accessories. Backed by CareFusion.

SUPPORT SYSTEMS
Ekso Bionics (2005, Richmond, IPO) – Bionic exoskeleton for people with paralysis. Went public in 2014.
BionX Medical (2007, Bedford, $75M) – Prosthetic device to aid movement of lower-limb amputees. Backed by Sigma Partners, General Catalyst, WFD Ventures and Gilde Healthcare.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates, visit the Medical Devices feed.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – CONSUMER HEALTHTECH

• Care.com, a marketplace connecting caregivers with care seekers, has raised $46.35M investment from Google Capital. Link
• Honor, an internet-first caregiver service provider for elderly care, has raised $42M in a Series B round led by Thrive Capital with participation from 8VC, Andreessen Horowitz, and Syno Capital. Link
• Spirometrix, Company providing solutions for monitoring & managing chronic respiratory diseases, has raised $17.4M in Series C round led by Shanghai Fosun Pharmaceutical, NGK Spark Plug, South Valley Angels, Iconical, Ohio Innovation Foundation, and Carmen Innovation. Link
• Progyny, an in-vitro fertilization, and fertility-focused digital health company has raised $14.7M in Series B round led by Kleiner Perkins Caufield and Byers, Mellon, SR One, TPG Biotech and Union Grove Venture Partners. Link
• Talkspace, telemedicine company targeting mental health, has raised $15 million in a round led by Norwest Venture Partners, Spark Capital, Soft Bank, Metamorphic Ventures, and TheTime. Link
• HealthKart, an online store for consumer health products, has raised $12M in a Series E round led by Sequoia Capital India and Kae Capital. Link
• Akili Interactive Labs, gamified cognitive digital therapeutic solution provider, has raised $12M in Series B round led by M Ventures, and the venture arm of Amgen joined existing investors, which include Pfizer and Shire Pharmaceuticals. Link
• 1mg, a digital healthcare services provider, has acquired Medd, a diagnostics and imaging tests marketplace, in an undisclosed deal. Link
• Withings, the connected device maker recently acquired by Nokia Technologies, has received FDA 510(k) clearance for Withings Thermo, WiFi-enabled thermometer. Also launched their device for consumers. Link, Link
• Wing, an app-connected spirometer of Sparo Labs, has received an over-the-counter clearance. Link
• Medtronic has received a CE Mark for its Guardian Connect mobile continuous glucose monitor (CGM) and app. Link
• DarioHealth, the developer of smart diabetes management solution, has begun offering its solution direct to the consumer in Australia. Link
• Quest Diagnostics, the diagnostic information company, has launched an iPad-based cognitive assessment tool to aid doctors in diagnosis, assessment and care management of people with cognitive dysfunction. Link
• WebMD began testing their new app – WemRx, due to declining traffic in the form of Google referrals. Link
• Consumer DNA data from 23nadME has yielded a breakthrough in the search for depression genes. Link

SOME INTERESTING STARTUPS FOUND

LEADER BOARD – CONSUMER HEALTH TECH

PERSONAL HEALTH MANAGEMENT

PATIENT EDUCATION
Information Portal
WebMD (1996, NYC, IPO) – Online platform providing health-related information to consumers and healthcare professionals. Went public in 2005.
Healthline Networks (2005, SF, $154M) – Health information portal. Also started providing appointment booking service through the platform by acquiring YourDoctor. Backed by Summit Partners, Trinity Capital Investment, Investor Growth Capital, Reed Elsevier Ventures, Vintage Point Capital Partners, Kaiser Permanente Ventures and U.S. News.

Community
DYX (2000, Beijing, $82M) – Online social media platform for people providing pharmaceuticals and healthcare information. Backed by Tencent, Shunwei, DCM.
Sharecare (2010, Atlanta, $39M) –  A social platform that allows people to ask, learn and act upon questions of health and wellness to the experts. Backed by NEV, Wellington, Tomorrow Ventures, Galen Partners, Heritage Group, andTrinity Health.

PERSONALIZED ADVICE
Your.MD (2013, London, $7M) – Mobile app which uses AI and Machine Learning technology to give personalized feedback to individuals as they speak or type their query. Backed by Smedvig.

MONITORING
Dayima (2012, Beijing, $66M) – App for period tracking and women’s health. It predicts period cycles based on past patterns, offering health tips on avoiding cramps and premenstrual syndromes, and links to an online forum where users can exchange their experiences on parenting, beauty, etc. Backed by By-Health, Haitong, BAI, Ce Yun Ventures, Sequoia, and ZhenFund.
TelCare (2008, Bethesda, $63.5M) – Provides a wireless blood glucose meter with two-way messaging, that transmits to a care management server, along with a suite of iPhone and Android apps. Backed by Qualcomm Ventures and Sequoia.

DIY DIAGNOSTIC SOLUTIONS
Scanadu (2011, Mountain View, $47.5M) – Makes medical devices for measuring body vitals. Backed by AME Cloud Ventures, Relay Ventures, Three leaf Ventures, Tencent, CBC Capitals, Fosun, IGlobe Partners, Vegastech Fund, Mindful Investors, Redmile Group and Broe.
Kinsa (2012, NYC, $11.5M) – Smart thermometer. Backed by KPCB, FirstMark Capital, and Founder Collective.

THERAPEUTIC SOLUTIONS
HeadSpace (2010, LA, $39M) – Provider of online guided meditation resources, accessible to users through the company’s website and via a mobile app. Backed by Advancit capital, Allen investments, Breyer Capital, Broadway Video, Deerfield, WME entertainment.
Chrono Therapeutics (2004, Waltham, $32M) – Device with programmable passive transdermal drug delivery for smoking cessation. Backed by National Cancer Institute, RockHealth, Canaan Partners, 5AM Ventures, Fountain Healthcare Partners, Mayo Clinic, and GE Ventures.

MEDICATION ADHERENCE
Mango Health (2012, SF, $8M) – Mobile app that helps consumers comply with their medication through games. Backed by KPCB, Bullpen capital, First Round Capital, Floodgate, RockHealth, and Baseline Ventures.
MediSafe (2012, Boston, $7M) – App for medication adherence. Backed by Qualcomm Ventures, SevenVentures, Lool Ventures, Pitango Venture Capital, 7wire Ventures, and TriVentures.

PERSONAL HEALTH RECORDS
CareSync (2011, Wesley Chapel, $22M) – The web and mobile application which allows patients to collect their electronic health records from different health care providers. Backed by Merck GHI, Greycroft, HMC, Tullis Health Investors, Clearwell group, and CDH Solutions.
CareZone (2010, San Francisco, $13M) – Personal health information log book. Backed by NEA, and Catamount Ventures.

HEALTHCARE DELIVERY

DOCTORS
Telemedicine
TelaDoc (2002, Dallas, IPO) – Telemedicine provider offering web and mobile based video consultations. IPO June 2015.
AmericanWell (2006, Boston, $123M) – Telehealth platform that connects users with doctors over the video feed. Backed by Inventures Alliance Management Company.

Homecare
Pager (2014, NYC, $24M) – Mobile app for on-demand doctor house call. Backed by NEA, Summation Health Ventures, Goodwater Capital, Montage Ventures, Lux capital.
Heal (2014, LA, $10M) – Mobile app for on-demand home visits for a family doctor. Backed by Slow Ventures, Pritzker Group, March CP.

Appointment booking
Guahao (2010, Hangzhou, $536M) – Online platform for appointment booking with doctors and a healthcare information portal. Backed by Tencent, GS, HillHouse Capital, Fosun, CBD Capital, Morningside Ventures, Qiming Venture Partners, and Henderson Shandong Tiyanye Co.
ZocDoc (2007, NYC, $225M) – An online platform which helps users to find a nearby health practitioner and instantly book an appointment online. Also provides scheduling software to providers. Backed by Atomico, Founders Fund, Baillie Gifford, GS, Khosla Ventures, DST Global Solutions, SV Angel.

DIAGNOSTICS

DxLabs
Theranos (2003, Palo Alto, $492M) – Blood testing solution which claims to provide fast and high-quality tests at 1/1,000 sample size of the typical blood draw, directly marketed to consumers. Backed by ATA Ventures, DFJ, and Continental Ventures.

Dx Kits
Ancestry (1983, Provo, IPO, Acq.) – Website offering family history information, historical records, and other genealogical information. Enables users to create their family tree and helps them discover, preserve and share their family history.
23andMe (2006, SF, $232M) – A human genome research company enabling customers to study their ancestry, genealogy, and inherited traits. Backed by Google Ventures, MPM Capital, NEA, JJDC and Mohr Davidow Ventures.

Marketplace
MD Save (2012, Brentwood, $15.5M) – Online marketplace providing discovery and appointment booking facility for healthcare services. Backed by MTS Health Investors.
WellnessFX (2010, SF, $6M) – An online platform which allows users to search for diagnostic tests, book appointments and do transactions online. Users provide samples offline and get reports online. Also provides training to monitor personal health. Backed by Javelin Ventures, Floodgate, Voyager Capital, and HealthTech Capital.

HEALTH INSURANCE

Internet-first Insurance providers
Oscar Health (2012, New York City, $727.5M) –  An internet first health insurance provider that uses digital healthcare solutions to keep its members healthy. Backed by Thrive Capital, Founders Fund, General Catalyst, Khosla Venters, Red Swan, BoxGroup, Goldman Sachs, Wellington, Google Capital, Lakestar, and Fidelity International.

Aggregator 
GoHealth Insurance (2001, Chicago, $50M) – Online price comparison and shopping portal for health insurance. Backed by NEP.
Gravie (2013, Minneapolis, $26M) – Online health insurance marketplace for consumers to choose and buy insurance, pay for it and manage all healthcare expenses at one place. Backed by Aberdare ventures, Split Rock Partners, and Firstmark Capital.

PHARMACY
7LK (2011, Guangzhou, $149M) – Online retailer of non-prescription drugs and health supplements such as pharmaceuticals, medical devices, and medical products. Backed by Grandyangtze, TusPark Ventures, and Govtor.
Yiyao (2010, Guangzhou, $72M) – Online drug store that sells over-the-counter medications, traditional Chinese remedies, and a variety of other health products.
PillPack (2013, Cambridge, $63M) – Mobile app-enabled telepharmacy service which periodically sends the required medications to the user. Backed by Accel Partners, Sherpa Ventures, CRV, Menlo VC, Atlas Ventures, Slow ventures, Highline VP, QueensBridge VP, Founder Collective, IDEO, and Techstarts.

CAREGIVERS

Marketplace
Care.com (2006, Waltham, IPO) – Online marketplace connecting families requiring babysitters and nannies (for children, senior adults or disabled), pet care, housekeeping with caregivers.
HomeHero (2013, Santa Monica, $23M) –  Web-based marketplace, which helps families find, hire and manage in-home care for seniors. Backed by Tencent, Social Capital, Graham Holdings, and Science.

Own-Fleet
HomeTeam (2013, Manhattan, $43.5M) – An online platform which allows people expert caregiver matching and a care team to promote healthy & active days. Backed by Kaiser Permanente Ventures, Oak HC/FT, Lux Capital, AI Ventures, and Recruit Strategic Partners.
Honor (2014, SF, $62M) – The web and mobile-based platform that allows users to find and book caregiver for elderly people. Backed by Andreessen Horowitz, RockHealth, Homebrew, True Ventures, and Kapor Capital.

MEDICAL TOURISM FACILITATOR
Medigo (2013, Berlin, $12M) – An online marketplace that facilitates searching, booking and arranging medical travel. Backed by Atlantic Labs, and Accel.

CLINICAL TRIAL ENROLLMENT
CureForward (2014, Cambridge, $19M) – Online clinical trial enrollment platform and DNA mapping from partnered labs. Backed by Apple Tree Partners.
TrialReach (2009, Richmond, $18M) – Search engine for clinical trials which helps patients to explore, understand and access clinical trials. Backed by Octopus Ventures, Amadeus Capital, and Smedvig Capital

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates, visit the Consumer HealthTech feed.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – HEALTHCARE ANALYTICS

• Viewics, a provider of business intelligence and analytics solutions to enhance operational, financial and clinical outcomes, secured $10.5M Series B funding. Link
• WiserCare, a provider of web-based decision support system for patients and doctors, raised $2.66M funding. Link
  
• Sequence Bio, a data-driven precision medicine company, secured $3M Seed financing led by Data Collective (DCVC). Link
  
• CareSkore, a provider of web-based predictive analytics platform for hospitals to manage patient populations, raised $4.3M funding. Link
  
• N-of-One, a provider of precision medicine oncology decision support tools, received $7m in Series B funding. Link
• Informatics In Context, a cloud-based clinical analytics company that automates and streamlines the patient prior authorization process, received $266K debt financing. Link
• Wellcentive, a provider of population health management and data analytic solutions is acquired by Royal Philips. Link

SOME INTERESTING STARTUPS FOUND

Passify (2016, Atlanta) – Provides data-driven healthcare, research and communication solutions for physicians, patients and researchers.
Dateva (2016, Toronto) – Offers health data integration platform to provide health insights to individuals and healthcare organisations.

LEADER BOARD – HEALTHCARE ANALYTICS

Suite Solutions
Inovalon (1998, Bowie, IPO) – Cloud-based analytics platform for clinical, financial and quality insights. Went public in 2015.
Evolent Health (2011, Arlington, IPO) – An integrated platform for population health, financial and operational analytics. Went public in 2015.
Flatiron Health (2012, NYC, $314M) – Cloud-based Cancer care platform for clinical, financial and operational intelligence. Backed by Google Ventures, Roche, First Round Capital, Social Capital, SV Angels and more.
Health Catalyst (2008, Salt Lake City, $237M) – A suite of health analytics and data management solutions to help identify care gaps and support process improvement. Backed by Sequoia Capital, Norwest Venture Partners, Sands Capital Ventures, Sorenson Capital and more.

Clinical Analytics
Proteus Digital Health (2001, Redwood City, $404M) – Medication adherence platform using sensor-enabled pills, biometric sensor patch and data analytics. Backed by Novartis, Medtronic, Oracle, KP Ventures.
Imaging Advantage (2007, Santa Monica, $295M) – Cloud-based clinical decision support tool for radiologists. Backed by Goldman Sachs, Brightwood Capital Advisors and CRG.
Heart Flow (2007, Redwood City, $227M) – Non-invasive decision support tool for diagnosing blood flow blockages in the heart. Backed by Capricorn Investment Group and more.
Welltok (2009, Denver, $151.5M) – PaaS based analytics platform for health optimization and population health management. Backed by Qualcomm Ventures, EMCAP partners, Interwest Partners, Bessemar Venture Capital.

Financial Analytics
MediGain (2002, Plano, $46M) – Analytics tools for revenue cycle management, billing and reimbursement. Backed by Prudential Capital Partners.
Apixio (2009, San Mateo, $42M) – Cognitive computing platform for risk adjustment coding. Backed by SSM Partners, First Analysis and Bain Capital Ventures.
Truveris (2009, NYC, $27M) – SaaS-based platform for prescription claims analytics and pharmacy data validation. Backed by New Leaf Venture Partners,Tribeca Venture Partners, First Round, New Atlantic Ventures and more.
LaunchPoint (2008, Rolling Meadows, $26M) – Cloud-based healthcare analytics platform for payment integrity solutions. Backed by Carrick Capital Partners.

Operational Analytics
Evariant (2008, Farmington, $68.5M) – CRM analytics platform for digital marketing and patient engagement. Backed by Goldman Sachs, Lightspeed Venture Partners, Health Enterprise Partners, Dignity Health and Salesforce Ventures.
Kyruus (2010, Boston, $56M) – Referral management solutions using analytics and data mining. Backed by Venrock, Mckesson Ventures, New Leaf Venture Partners, Highland Capital Partners and more.
OnShift (2008, Cleveland, $30M) – SaaS based staff scheduling software that predicts and prevents overtime and under-staffing. Backed by Health Velocity Capital, HLM Venture Partners, Draper Triangle, West Capital Advisors and more.
PatientPop (2014, Santa Monica, $24M) – End-to-end marketing platform that uses analytics for performance measurement. Backed by Toba Capital, Athena Health and Silicon Valley Bank.
Binary Fountain (2003, Mclean, $22M) – Cloud-based platform for analyzing patient feedback from social media, surveys and online sites. Backed by HLM Venture Partners, Pioneer Venture Partners and Providence Health & Services.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates, visit the Healthcare Analytics feed.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – HEALTHCARE IT

• Kit Check, an automated cloud software for managing hospital pharmacy kits raised a funding of $15M in Series C with Baxter Ventures leading the round and other investors being Black Granite Capital, New Leaf Venture Partners, Easton Capital Management, LionBird and Sands Capital Ventures. Link
• Magic Software Enterprises a global provider of software platforms for enterprise mobility, cloud applications, and business integration acquired 60% equity interest in Roshtov Software Industries, the developer of the Clicks development platform which is used in the design and management of patient-file oriented software solutions for managed care and large-scale healthcare providers. Link
• LeanTaas, a SaaS-based analytic application to improve operational performance of hospitals and clinics raised a funding of $9M in Series B. Link
• Reflexion, provides Microsoft’s Kinect motion sensing system to doctors, in order to track patient’s adherence to the prescribed rehabilitation plan, raised a funding of $18M in Series B. Link
• HealthPrize Technologies, a medication adherence platform based on reward system raised an undisclosed amount in Series B from Mansa Equity. Link
• NoemaLife, which offers clinical and hospital information systems was acquired by Dedalus group. Link
• NeuroVision, integrated neuroscience company that focuses on designing diagnostic tests and biomarkers for early detection and monitoring of amyloid pathology related to Alzheimer’s Disease raised a funding of $5M in Series B with Wildcat Capital Management leading the round. Link
• Healthiest You which provides doctor appointment booking, telemedicine, wellness, price comparison of drugs and medical procedures, and health plan information on a single platform was acquired by Teladoc for $125M. Link
• Medsphere Systems, a provider of open source software for the healthcare industry raised a funding of $15.3M in Series D. Link
• Cloud9Ortho, cloud-based orthodontic practice management solution raised a funding of $5.06M in Series A. Link
• Network Locum, an online network that matches General Practitioner (GP) locums and practices raised a funding of $7M in Series B from BGF Ventures. Link
• Virta Health which develops and delivers clinically proven and individualized therapies to restore metabolic health in chronic disease patients raised a funding of $28M. Link
• Staywell, a company providing population health management, consumer engagement, and training, and patient education solutions was acquired by Healthcare Services & Solutions LLC, a subsidiary of Merck & Co. Link
• ESO solutions, which provides suite solution of workflow management and health information exchange raised a funding of $17.6M in Series C from Accel-KKR. Link
• Central Logic, a web-based hospital transfer center solution that helps hospitals and healthcare systems manage and optimize patient flow raised a funding of $5.9M in Series C led by Iron Gate Capital of Boulder, Colo. and Mercato Partners of Salt Lake City, Utah. Link
• Marathon Health, a provider of health and wellness solutions for employers and members raised PE funding of $30M from Goldman Sachs. Link
• Caremerge, a provider of web and mobile communication & care coordination solutions for senior living communities raised a funding of $14M led by Insight Venture Partners, with participation from previous investors Grażyna Kulczyk, Cambia Health Solutions, Ziegler LinkAge Longevity Fund, GE Ventures, and Arsenal Venture Partners. Link
• Forward, a stealth startup, as of June 2016 claims to use sensors to rethink the healthcare experience raised a funding of $29.5M. Link
• Valence Health, a provider of clinical integration, population health, and value-based care solutions was acquired by Evolent Health for $145M. Link
• Docent Health, a creator of software and mobile applications that will help organize and monitor every aspect of an individual’s hospital visit raised a funding of $15M co-led by Bessemer Venture Partners, New Enterprise Associates (NEA) and Maverick Ventures. Link
• Endotronix, which is developing the Endotronix Care Management Solution to communicate pressures that accurately measure cardiac function and provide software and services to personalize the patient care experience raised a funding of $32M led by Lumira Capital. Link
• Azalea Health provides a platform which is electronic health records with integrated telehealth functionality as well as personal health records and mobile health applications raised a funding of $10.5M series B led by Kayne Partners. Link
• 98point6, an early-stage technology company in stealth mode raised a funding of $11M. Link
• Wellcentive, a healthcare intelligence solution suite that provides solutions including population management, clinical decision support was acquired by Philips. Link
• Akili Interactive Labs, a provider of gamified cognitive therapeutics raised a funding of $11.9M in series B led by the Dutch subsidiary of Merck Ventures, known as M Ventures in the US and Canada, and the venture arm of Amgen along with existing investors, which include Pfizer and Shire Pharmaceuticals. Link
• AristaMD, a digital health company focused on improving the specialty referral process raised a funding of $11M led by Avalon Ventures, with participation from Correlation Ventures. Link
• N-of-One, a molecular decision support company providing clinicians with clinically meaningful interpretation of molecular test results raised a funding of $7M in series B led by Providence Ventures and Excel Venture Management. Link
• Big Health, a healthcare company that delivers personalized behavioral medicine via web and mobile raised a funding of $12M led by Octopus Ventures, Kaiser Permanente Ventures, Index. Link
• Viewics Health Insighter, a visualization, and analytics solution provides clinical, operational, sales, and marketing teams with interactive dashboards for making day-to-day decisions raised a funding of $10.5M led by existing investor Canvas Ventures and new investor Roche Venture Fund. Link
• StatRad, offers teleradiology services to the providers operated by radiologists raised a funding of $13M. Link
• ElationEMR, an online electronic medical record (EMR) system raised a funding of $15M led by DFJ, with participation from Martha Marsh and Charlie Cheever. Link
• CareSkore, a web based predictive analytics driven platform helps hospitals, health systems, and ACOs raised a funding of $4.3M. Link
• Morrisey Associates, a provider or software which includes web-based applications for credentialing and privileging,care management and practitioner performance reporting was acquired by HealthStream for $48M. Link
• Press Ganey, provides patient experience measurement, performance analytics and strategic advisory solutions to healthcare organizations was acquired by $2.35B by EQT Equity Investment. Link
• Accolade, a provider of consumer healthcare engagement and influence solution for large self-insured employers and payer organizations raised a funding of $55M to complete the series E round of $93M started in July 2015 led by Andreessen Horowitz, with participation from Madrona Venture Group. Link

SOME INTERESTING STARTUPS FOUND

Clovi (2016, Toronto) – Offers tools to measure and track ROI on wellness programs for employers.
3D Bolus (2016, Halifax) – Provides software application that provides practitioners with turn-key software that enables printing of uniform thickness bolus
Bainbridge Health (2016, Philadelphia) – Provides a clinical intelligence & data analytics platform to monitor patient safety & reduce medication errors
Forward (2016, SFO) – Claims to use sensors to rethink the healthcare experience

LEADER BOARD –  HEALTHCARE IT

VALUE BASED CARE
Evolent Health (2011, Virginia, IPO) – Provides healthcare technologies and services that improve clinical, operational and business outcomes. The company’s services include providing customers with a population. Went public in 2015.
Privia Health (2007, Virginia, $419M) – Builds and enables physician groups and clinically integrated provider networks using technology, team-based care, and wellness programs to help doctors to manage the health of their populations. Backed by Goldman Sachs, Pamplona Funds, Cardinal Partners, Brighton Health, Health Enterprise Partners and Morgan Noble.
Lumeris (2001, Maryland Heights, $211M) – Provider of population health management solutions to health systems, payers and providers. Backed by BlueCross BlueShield Venture Partners, Camden Partners, Kleiner Perkins Caufield & Byers and Sandbox industries.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – BIOPHARMA

• GSK, Roche, Novo back Immuno-Oncology startup Tioma Therapeutics in $86M Series A. Link
• Roche, Eleven Bio ink $270M exclusive licensing deal. Link
• Sorrento’s subsidiary Scintilla Pharma snapped up Semnur for $200M. Link
• Protagonist raises $90M IPO as it upsizes offering. Link
• Allergan pays $95M for ForSight VISION5, eye insert for glaucoma. Link
• Genmab scores $277M DuoBody technology tie-up with Gilead. Link
• AstraZeneca bets another $140M on Moderna’s messenger drugs. Link
• GSK inks money-back guarantee on $665K Strimvelis, blazing a trail for gene-therapy pricing. Link
• Amgen does preclinical I/O tie-up with small cap Advaxis for up to $540M, stock jumps 28%. Link
• Pfizer acquires gene therapy company Bamboo Therapeutics for $150M upfront, and up to an additional $495M in milestone payments. Link

SOME INTERESTING STARTUPS FOUND

LEADER BOARD – BIOPHARMA

Immunotherapy
Juno Therapeutics (2013, Seattle, IPO) – Immunotherapies based on chimeric antigen receptor and T cell receptor technologies to genetically engineer T cells to recognize and kill cancer cells. Went public in 2014. Backed by Alaska Permanent Fund, ARCH Venture Partners, Venrock & Bezos Expeditions.
DBV Technologies (2002, Bagneux, IPO) – Epicutaneous immunotherapy for the treatment of various kinds of food and pediatric allergy. Went public in 2012. Backed by InnoBio Fund, Lundbeckfond Ventures and others.
Stemcentrx (2008, SF, $500M, Acq.) – Antibodies and antibody-drug conjugates (ADCs) to target cancer stem cells. Backed by Founders Fund, Artis Ventures and Fidelity Investments.
Immunocore (2008, Abingdon, $320M) – Developing Immune mobilizing mTCR Against Cancer (IImmTACs) that enable the immune system to recognize and kill cancerous or bacterially/virally infected cells. Backed by Eli Lilly, Malin Corporation, and Woodford Investment Management.

Gene Therapy
Alnylam Pharmaceuticals (Cambridge, 2002, IPO) – Developing therapeutics based on RNA interference (RNAi) for the treatment of rare genetic & cardio-metabolic diseases. Went public in 2004. Backed by Takeda Pharmaceutical, Genzyme and others.
Audentes Therapeutics (2013, SF, IPO) – Developing treatments for rare muscle diseases using adeno-associated virus (AAV) gene therapy technology. Backed by OrbiMed Advisors, Deerfield Capital Management, Redmile Group, Sofinnova Ventures and others. Went public in 2016.
Editas Medicine (2013, Cambridge, IPO) – Developing therapeutics based on CRISPR/Cas genome editing technology to treat the underlying cause of a broad range of diseases at the genetic level. Backed by Flagship Ventures, Polaris Partners, Third Rock Ventures and others. Went public in 2016.
Moderna Therapeutics (2010, Cambridge, $1.06B) – Messenger RNA-based therapeutics that produces human proteins or antibodies inside patient cells for rare diseases & cancer. Backed by Alexion Pharmaceuticals, Flagship Ventures, and others.

Microbiome Therapy
Seres Therapeutics (2010, Cambridge, IPO) – Ecobiotic microbiome therapeutics to treat dysbiosis in the colonic microbiome. Went public in 2015. Backed by Flagship Ventures, Enso Ventures, Nestle Health Science, Mayo Clinic and Alexandria Venture Investments.
C3 Jian (2005, LA, $105M) – Pathogen-specific antimicrobial peptide therapeutics to treat & prevent diseases caused by microbial dysbiosis. Backed by Renaissance Health Service Corp., Wyssta Investments, and Corvesta.
Evelo Therapeutics (2015, Cambridge, $35M) – Discovering & developing Oncobiotic therapies through the systematic understanding of cancer associated microbiome & bacterial immune activators. Backed by Flagship Ventures.

Synthetic Biology
Intrexon Corporation (1998, Blacksburg, IPO) – Employs modular DNA control systems to enhance capabilities, improve safety & lower cost in human therapeutics, protein production, industrial products, agricultural biotechnology, and animal science. Went public in 2013. Backed by Third Security and NewVa Capital Partners.
Ginkgo Bioworks (2008, Boston, $154M) – Engineering microbes to produce cultured ingredients such as flavors, fragrances, cosmetics, and sweeteners. Backed by Viking Global Investors, Felicis Ventures, OS Fund and others.
Twist Bioscience (2013, SF, $133M) – Developing a semiconductor-based system for synthetic DNA manufacturing. Backed by Illumina, Tao Venture Partners, ARCH Venture Partners and Paladin Capital Group.

Cell Therapy & Regenerative Medicine
Humacyte (2004, Morrisville, $150M) – Developing human tissue-based products for vascular disease & replacement of anatomical conduits. Backed by Access Industries, Bangkok bank, Pacific Eagle Asset Management and Reignwood Group. 
Gamida Cell (1998, Jerusalem, $95M) – Developing treatments for orphan hematological diseases & malignancies using stem cells and NK cells. Backed by Auriga Partners, Israel Healthcare Ventures and Novartis.
Xeltis (2006, Zurich, $66M) – Developing bioabsorbable synthetic heart valves & vascular grafts aimed at restoring healthy valve and vessels. Backed by Kurma Life Science Partners, Life Sciences Partners and VI Partners.

Protein Therapy
Semma Therapeutics (2014, Boston, $44M) – Developing a cell therapy for Type 1 diabetes. Backed by MPM Capital, Fidelity Biosciences, ARCH Venture Partners, and Medtronic.
 Aileron Therapeutics (2005, Cambridge, $121M) – Developing stapled peptides to modulate intracellular protein-protein interactions for the treatment of cancer. Backed by Aju IB Investment, SR One, Novartis Venture Fund and others.
Aeglea Biotherapeutics (2013, Austin, $68M) – Engineering human amino acid degrading enzymes for the treatment of inborn errors of metabolism and cancer. Backed by Novartis Venture Fund, Lilly Ventures and others.

Omics
Oxford Nanopore Technologies (2005, Oxford, $408.5M) – Developing nanopore-based electronic systems for analysis of single molecules including DNA, RNA, and proteins. Backed by IP Group, Illumina, Lansdowne Partners and others.
Human Longevity (2013, San Diego, $300M) – Developing and applying large-scale computing and machine learning to advance personalized medicine.  Backed by Illumina, Celgene, GE Ventures and others. 
iCarbonX (2013, Shenzhen, $215M) – Big Data and AI-powered platform to analyze omics data along with phenotypic, social and environmental information. Backed by Tencent, Vcanbio and China Bridge Capital.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – TELEMEDICINE

• Ping An Good Doctor, an online platform to consult doctors remotely, completed a $500M Series A round of financing. Link
• Talkspace, an NYC-based provider of an online therapy platform, raised $15M in Series B funding led by Norwest Venture Partners. Link
• RetraceHealth, a concierge care provider using nurse practitioners, was funded $7M in Series A round of funding. Link
• Vios Medical, a remote patient monitoring system, raised $3.98M in Series A round of funding. Link
• WeCounsel Solutions, a Chattanooga-based telemedicine software company, closed a Series A equity funding of $3.5M. Link
• Avizia, a real-time video collaboration platform, raised $3.1M in Series B round of funding. Link
• ReGroup Therapy, an on-demand provider of virtual mental health teams to health entities, raised over $1.8M in a seed round. Link
• Fruit Street Health, a telehealth software solutions provider, raised $1.4M in crowdfunding from 120 physicians. Link
• PurpleHealth, an on-demand health platform, raised $100k from Katabole Technology Venture. Link
• iCliniq, an online doctor consultation platform, raised an undisclosed amount in an angel round from an Erode-based laparoscopic surgeon MadhanKumar Madathupalayam. Link
• Visit, Delhi-based on-demand healthcare service provider raised an undisclosed amount in seed funding from tech company MapmyIndia. Link
• Connecture, a technology company that builds online health insurance marketplaces, acquired ConnectedHealth, a platform that makes it easier for consumers and employees to shop for personalized health insurance online. Link

SOME INTERESTING STARTUPS FOUND

MyCampusDoc (2015, Dallas) – Provides college students with a discount card to assist them with their medical needs including teleconsultation.

LEADER BOARD – TELEMEDICINE

Tele-Consultation
Teladoc (2002, Dallas, IPO) – Telemedicine provider offering web and mobile based video consultation. Backed by Cardinal Partners, HLM Venture Partners, Trident Capital, New Capital Partners, Jafco Ventures, Kleiner Perkins Caufield & Byers, Greenspring Associates, BNY Mellon, Questmark Partners, FLAG Capital Management. Went public in June 2015.
American Well (2006, Boston, $123M) – Telehealth platform that connects users with doctors. Backed by Inventure Partners.
Specialists On Call (2004, Reston, $112M) – Telemedicine services for Tele-Neurology, Tele-Psychiatry and Tele-Intensivist. Backed by Warburg Pincus.
Doctor On Demand (2012, SF, $87M) – Telemedicine services based on a pay-per-use model. Backed by Venrock, Shasta Ventures, Qualcomm Ventures.
MDLIVE (2009, Sunrise, $74M) – Online and on-demand telemedicine services. Backed by Bedford Funding, Heritage Group, Sutter Health, Kanye Capital.

Tele-Monitoring
iRhythm Technologies (2006, SF, $95M) Remote cardiac rhythm monitoring device. Backed by Mohr Davidow Ventures.
AirStrip (2003, San Antonio, $65M) Mobility solutions for providers to access patient data remotely. Backed by Wellcome Trust, Sequoia Capital, West Health Institute, Qualcomm Ventures.
Watermark Medical (2008, Boca Raton, $45M) Home sleep testing solutions to determine presence and severity of obstructive sleep apnea. Merged with SleepMed. Backed by Ballast Point Ventures.
MD Revolution (2011, San Diego, $34M) Platform for healthcare providers to predict and prevent chronic disease via behaviour change. Backed by Jump Capital.
Healthsense (2001, Mendota, $33M) Remote monitoring, emergency calls and wellness management solutions. Backed by Radius Ventures, Merck & Co., Mansa Capital, Merck Global Health Innovation Fund.

Tele-Rehabilitation
Pursuant Health (2007, Atlanta, $29M) Interactive healthcare platforms and kiosks. Backed by WellPoint, Novartis, Dell, Coinstar.

Tech Enablers
InTouch Health (2002, Santa Barbara, $34M) Proprietary communications and mobile robotic platform. Backed by Acacia VP, iRobot, Beringea.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates visit Telemedicine feeds

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – DIAGNOSTICS

• Omicia, developer of clinical genome interpretation software, raises $23M Series B, from UPMC, Roche, LDV Partners, along with returning investors. Link
• Liquid biopsy company Freenome closes a $5.5M Series A round, led by Andreessen Horowitz. Link
• Owlstone Medical, which develops breath-based screening tests for cancer, closes a $7M round of financing. Link
• NeuroVision Imaging, developer of diagnostics solutions for Alzheimer’s disease, raises $5M in Series B financing. Link
• Perthera, a precision diagnostics company for cancer, closes a $8.7M Series A round. Link
• Spirometrix, which develops point-of-care breathalyzers, raises $17.4M Series C. Link
• Philips acquires digital pathology company PathXL for an undisclosed amount. Link
• Foundation Medicine and AstraZeneca sign a deal to develop companion diagnostics for ovarian cancer. Link
• UPenn to lead consortium with $10.8M in NIH grant funding to study genetic basis of Alzheimer’s. Link
• France jumps on the precision medicine bandwagon; announce a $670M initiative to support genomics and personalized medicine. Link
  

SOME INTERESTING STARTUPS FOUND

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – HEALTHCARE IT

• Kit Check, an automated cloud software for managing hospital pharmacy kits raised a funding of $15M in Series C with Baxter Ventures leading the round and other investors being Black Granite Capital, New Leaf Venture Partners, Easton Capital Management, LionBird and Sands Capital Ventures. Link
• Magic Software Enterprises a global provider of software platforms for enterprise mobility, cloud applications, and business integration acquired 60% equity interest in Roshtov Software Industries, the developer of the Clicks development platform which is used in the design and management of patient-file oriented software solutions for managed care and large-scale healthcare providers. Link
• LeanTaas, a SaaS-based analytic application to improve operational performance of hospitals and clinics raised a funding of $9M in Series B. Link
• Reflexion, provides Microsoft’s Kinect motion sensing system to doctors, in order to track patient’s adherence to the prescribed rehabilitation plan, raised a funding of $18M in Series B. Link
• HealthPrize Technologies, a medication adherence platform based on reward system raised an undisclosed amount in Series B from Mansa Equity. Link
• NoemaLife, which offers clinical and hospital information systems was acquired by Dedalus group. Link
• NeuroVision, integrated neuroscience company that focuses on designing diagnostic tests and biomarkers for early detection and monitoring of amyloid pathology related to Alzheimer’s Disease raised a funding of $5M in Series B with Wildcat Capital Management leading the round. Link
• Healthiest You which provides doctor appointment booking, telemedicine, wellness, price comparison of drugs and medical procedures, and health plan information on a single platform was acquired by Teladoc for $125M. Link
• Medsphere Systems, a provider of open source software for the healthcare industry raised a funding of $15.3M in Series D. Link
• Cloud9Ortho, cloud-based orthodontic practice management solution raised a funding of $5.06M in Series A. Link
• Network Locum, an online network that matches General Practitioner (GP) locums and practices raised a funding of $7M in Series B from BGF Ventures. Link
• Virta Health which develops and delivers clinically proven and individualized therapies to restore metabolic health in chronic disease patients raised a funding of $28M. Link
• Staywell, a company providing population health management, consumer engagement, and training, and patient education solutions was acquired by Healthcare Services & Solutions LLC, a subsidiary of Merck & Co. Link
• ESO solutions, which provides suite solution of workflow management and health information exchange raised a funding of $17.6M in Series C from Accel-KKR. Link
• Central Logic, a web-based hospital transfer center solution that helps hospitals and healthcare systems manage and optimize patient flow raised a funding of $5.9M in Series C led by Iron Gate Capital of Boulder, Colo. and Mercato Partners of Salt Lake City, Utah. Link
• Marathon Health, a provider of health and wellness solutions for employers and members raised PE funding of $30M from Goldman Sachs. Link
• Caremerge, a provider of web and mobile communication & care coordination solutions for senior living communities raised a funding of $14M led by Insight Venture Partners, with participation from previous investors Grażyna Kulczyk, Cambia Health Solutions, Ziegler LinkAge Longevity Fund, GE Ventures, and Arsenal Venture Partners. Link
• Forward, a stealth startup, as of June 2016 claims to use sensors to rethink the healthcare experience raised a funding of $29.5M. Link
• Valence Health, a provider of clinical integration, population health, and value-based care solutions was acquired by Evolent Health for $145M. Link
• Docent Health, a creator of software and mobile applications that will help organize and monitor every aspect of an individual’s hospital visit raised a funding of $15M co-led by Bessemer Venture Partners, New Enterprise Associates (NEA) and Maverick Ventures. Link
• Endotronix, which is developing the Endotronix Care Management Solution to communicate pressures that accurately measure cardiac function and provide software and services to personalize the patient care experience raised a funding of $32M led by Lumira Capital. Link
• Azalea Health provides a platform which is electronic health records with integrated telehealth functionality as well as personal health records and mobile health applications raised a funding of $10.5M series B led by Kayne Partners. Link
• 98point6, an early-stage technology company in stealth mode raised a funding of $11M. Link
• Wellcentive, a healthcare intelligence solution suite that provides solutions including population management, clinical decision support was acquired by Philips. Link
• Akili Interactive Labs, a provider of gamified cognitive therapeutics raised a funding of $11.9M in series B led by the Dutch subsidiary of Merck Ventures, known as M Ventures in the US and Canada, and the venture arm of Amgen along with existing investors, which include Pfizer and Shire Pharmaceuticals. Link
• AristaMD, a digital health company focused on improving the specialty referral process raised a funding of $11M led by Avalon Ventures, with participation from Correlation Ventures. Link
• N-of-One, a molecular decision support company providing clinicians with clinically meaningful interpretation of molecular test results raised a funding of $7M in series B led by Providence Ventures and Excel Venture Management. Link
• Big Health, a healthcare company that delivers personalized behavioral medicine via web and mobile raised a funding of $12M led by Octopus Ventures, Kaiser Permanente Ventures, Index. Link
• Viewics Health Insighter, a visualization, and analytics solution provides clinical, operational, sales, and marketing teams with interactive dashboards for making day-to-day decisions raised a funding of $10.5M led by existing investor Canvas Ventures and new investor Roche Venture Fund. Link
• StatRad, offers teleradiology services to the providers operated by radiologists raised a funding of $13M. Link
• ElationEMR, an online electronic medical record (EMR) system raised a funding of $15M led by DFJ, with participation from Martha Marsh and Charlie Cheever. Link
• CareSkore, a web based predictive analytics driven platform helps hospitals, health systems, and ACOs raised a funding of $4.3M. Link
• Morrisey Associates, a provider or software which includes web-based applications for credentialing and privileging,care management and practitioner performance reporting was acquired by HealthStream for $48M. Link
• Press Ganey, provides patient experience measurement, performance analytics and strategic advisory solutions to healthcare organizations was acquired by $2.35B by EQT Equity Investment. Link
• Accolade, a provider of consumer healthcare engagement and influence solution for large self-insured employers and payer organizations raised a funding of $55M to complete the series E round of $93M started in July 2015 led by Andreessen Horowitz, with participation from Madrona Venture Group. Link

SOME INTERESTING STARTUPS FOUND

Clovi (2016, Toronto) – Offers tools to measure and track ROI on wellness programs for employers.
3D Bolus (2016, Halifax) – Provides software application that provides practitioners with turn-key software that enables printing of uniform thickness bolus
Bainbridge Health (2016, Philadelphia) – Provides a clinical intelligence & data analytics platform to monitor patient safety & reduce medication errors
Forward (2016, SFO) – Claims to use sensors to rethink the healthcare experience

LEADER BOARD –  HEALTHCARE IT

VALUE BASED CARE
Evolent Health (2011, Virginia, IPO) – Provides healthcare technologies and services that improve clinical, operational and business outcomes. The company’s services include providing customers with a population. Went public in 2015.
Privia Health (2007, Virginia, $419M) – Builds and enables physician groups and clinically integrated provider networks using technology, team-based care, and wellness programs to help doctors to manage the health of their populations. Backed by Goldman Sachs, Pamplona Funds, Cardinal Partners, Brighton Health, Health Enterprise Partners and Morgan Noble.
Lumeris (2001, Maryland Heights, $211M) – Provider of population health management solutions to health systems, payers and providers. Backed by BlueCross BlueShield Venture Partners, Camden Partners, Kleiner Perkins Caufield & Byers and Sandbox industries.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – BIOPHARMA

• GSK, Roche, Novo back Immuno-Oncology startup Tioma Therapeutics in $86M Series A. Link
• Roche, Eleven Bio ink $270M exclusive licensing deal. Link
• Sorrento’s subsidiary Scintilla Pharma snapped up Semnur for $200M. Link
• Protagonist raises $90M IPO as it upsizes offering. Link
• Allergan pays $95M for ForSight VISION5, eye insert for glaucoma. Link
• Genmab scores $277M DuoBody technology tie-up with Gilead. Link
• AstraZeneca bets another $140M on Moderna’s messenger drugs. Link
• GSK inks money-back guarantee on $665K Strimvelis, blazing a trail for gene-therapy pricing. Link
• Amgen does preclinical I/O tie-up with small cap Advaxis for up to $540M, stock jumps 28%. Link
• Pfizer acquires gene therapy company Bamboo Therapeutics for $150M upfront, and up to an additional $495M in milestone payments. Link

SOME INTERESTING STARTUPS FOUND

LEADER BOARD – BIOPHARMA

Immunotherapy
Juno Therapeutics (2013, Seattle, IPO) – Immunotherapies based on chimeric antigen receptor and T cell receptor technologies to genetically engineer T cells to recognize and kill cancer cells. Went public in 2014. Backed by Alaska Permanent Fund, ARCH Venture Partners, Venrock & Bezos Expeditions.
DBV Technologies (2002, Bagneux, IPO) – Epicutaneous immunotherapy for the treatment of various kinds of food and pediatric allergy. Went public in 2012. Backed by InnoBio Fund, Lundbeckfond Ventures and others.
Stemcentrx (2008, SF, $500M, Acq.) – Antibodies and antibody-drug conjugates (ADCs) to target cancer stem cells. Backed by Founders Fund, Artis Ventures and Fidelity Investments.
Immunocore (2008, Abingdon, $320M) – Developing Immune mobilizing mTCR Against Cancer (IImmTACs) that enable the immune system to recognize and kill cancerous or bacterially/virally infected cells. Backed by Eli Lilly, Malin Corporation, and Woodford Investment Management.

Gene Therapy
Alnylam Pharmaceuticals (Cambridge, 2002, IPO) – Developing therapeutics based on RNA interference (RNAi) for the treatment of rare genetic & cardio-metabolic diseases. Went public in 2004. Backed by Takeda Pharmaceutical, Genzyme and others.
Audentes Therapeutics (2013, SF, IPO) – Developing treatments for rare muscle diseases using adeno-associated virus (AAV) gene therapy technology. Backed by OrbiMed Advisors, Deerfield Capital Management, Redmile Group, Sofinnova Ventures and others. Went public in 2016.
Editas Medicine (2013, Cambridge, IPO) – Developing therapeutics based on CRISPR/Cas genome editing technology to treat the underlying cause of a broad range of diseases at the genetic level. Backed by Flagship Ventures, Polaris Partners, Third Rock Ventures and others. Went public in 2016.
Moderna Therapeutics (2010, Cambridge, $1.06B) – Messenger RNA-based therapeutics that produces human proteins or antibodies inside patient cells for rare diseases & cancer. Backed by Alexion Pharmaceuticals, Flagship Ventures, and others.

Microbiome Therapy
Seres Therapeutics (2010, Cambridge, IPO) – Ecobiotic microbiome therapeutics to treat dysbiosis in the colonic microbiome. Went public in 2015. Backed by Flagship Ventures, Enso Ventures, Nestle Health Science, Mayo Clinic and Alexandria Venture Investments.
C3 Jian (2005, LA, $105M) – Pathogen-specific antimicrobial peptide therapeutics to treat & prevent diseases caused by microbial dysbiosis. Backed by Renaissance Health Service Corp., Wyssta Investments, and Corvesta.
Evelo Therapeutics (2015, Cambridge, $35M) – Discovering & developing Oncobiotic therapies through the systematic understanding of cancer associated microbiome & bacterial immune activators. Backed by Flagship Ventures.

Synthetic Biology
Intrexon Corporation (1998, Blacksburg, IPO) – Employs modular DNA control systems to enhance capabilities, improve safety & lower cost in human therapeutics, protein production, industrial products, agricultural biotechnology, and animal science. Went public in 2013. Backed by Third Security and NewVa Capital Partners.
Ginkgo Bioworks (2008, Boston, $154M) – Engineering microbes to produce cultured ingredients such as flavors, fragrances, cosmetics, and sweeteners. Backed by Viking Global Investors, Felicis Ventures, OS Fund and others.
Twist Bioscience (2013, SF, $133M) – Developing a semiconductor-based system for synthetic DNA manufacturing. Backed by Illumina, Tao Venture Partners, ARCH Venture Partners and Paladin Capital Group.

Cell Therapy & Regenerative Medicine
Humacyte (2004, Morrisville, $150M) – Developing human tissue-based products for vascular disease & replacement of anatomical conduits. Backed by Access Industries, Bangkok bank, Pacific Eagle Asset Management and Reignwood Group. 
Gamida Cell (1998, Jerusalem, $95M) – Developing treatments for orphan hematological diseases & malignancies using stem cells and NK cells. Backed by Auriga Partners, Israel Healthcare Ventures and Novartis.
Xeltis (2006, Zurich, $66M) – Developing bioabsorbable synthetic heart valves & vascular grafts aimed at restoring healthy valve and vessels. Backed by Kurma Life Science Partners, Life Sciences Partners and VI Partners.

Protein Therapy
Semma Therapeutics (2014, Boston, $44M) – Developing a cell therapy for Type 1 diabetes. Backed by MPM Capital, Fidelity Biosciences, ARCH Venture Partners, and Medtronic.
 Aileron Therapeutics (2005, Cambridge, $121M) – Developing stapled peptides to modulate intracellular protein-protein interactions for the treatment of cancer. Backed by Aju IB Investment, SR One, Novartis Venture Fund and others.
Aeglea Biotherapeutics (2013, Austin, $68M) – Engineering human amino acid degrading enzymes for the treatment of inborn errors of metabolism and cancer. Backed by Novartis Venture Fund, Lilly Ventures and others.

Omics
Oxford Nanopore Technologies (2005, Oxford, $408.5M) – Developing nanopore-based electronic systems for analysis of single molecules including DNA, RNA, and proteins. Backed by IP Group, Illumina, Lansdowne Partners and others.
Human Longevity (2013, San Diego, $300M) – Developing and applying large-scale computing and machine learning to advance personalized medicine.  Backed by Illumina, Celgene, GE Ventures and others. 
iCarbonX (2013, Shenzhen, $215M) – Big Data and AI-powered platform to analyze omics data along with phenotypic, social and environmental information. Backed by Tencent, Vcanbio and China Bridge Capital.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – LIFE SCIENCE – SOFTWARE

• Metabolon, a provider of bioinformatics solutions for biomarker discovery using metabolomics has raised $15 million from Essex Woodlands. Metabolon and Essex Woodlands have the ability to increase the purchase up to an additional $10 million, proceeds of which would be utilized to repurchase shares from existing investors. Link
• Inscopix, a startup developing brain mapping platform raised $10 million in a series A financing round led by Playground Ventures, with co-investment by AME Cloud Ventures and Floodgate Fund. Link
• Teckro, a provider of software solutions for clinical trials has raised $ 6 million in a series A funding round lead by Founders Fund. Link
• Riffyn, a provider of cloud-based research process design software has raised $3.2 million from Siemens Venture Capital. Link
• Ontoforce, provider of Disqover, a semantic search platform that integrated various life-sciences data has raised $ 2.33 million from LRM, Sofi fund, Luc Vauterin, Torsten Osthus and investors from American Life Science Innovation Fund (LSIF). Link
• Proscia, a provider of digital pathology software has raised $1 million in seed round led by Emerald Development Manager, with Robin Hood Ventures, TCP Venture Capital and A-Level Capital also participating in the funding round. Link
• Florence Healthcare, a company offering electronic data collection and management solutions for clinical trials has raised $1.7 million in seed funding round led by Bee Partners and accompanied by Bessemer Venture Partners, Green D fund, and Fitbit’s Vice President of Engineering, Will Crawford. Link
• Modulated Imaging, a provider of imaging and visualization tools has raised $0.5 million in a seed round led by Cove Fund accompanied by Hamamatsu Photonics KK through its wholly-owned subsidiary, Photonics Management Corporation. Link
• Phosphorus, a spin-off from Recombine Diagnostics developing genomics solutions has raised $10 million in a series A round led by FirstMark. Link
• Benchsci, a platform to search papers to find antibody usage data has graduated from FounderFuel’s Spring 2016 cohort and has received seed funding as a part of the program. Link
• Bioz, a search engine that indexes and tracks trends in the sciences by algorithmically analyzing research papers, has raised $3 million, in a funding round led by 5AM Ventures with participation from the Stanford StartX Fund, Astia Angels, investor Esther Dyson and others. Link
• iPug, a company using gamified, reward-based communications platform to deliver individualized public health campaigns, and recruit and engage participants in research studies and clinical trials has received funding from Zane Beckett and other investors.Link
• MicroDimensions, a software and service provider for automated image analysis for digital pathology has raised a seven-digit financing in a series A round led by Dr. Adriaan Hart de Ruijter with participation from High-Tech Gründerfonds, Bayern Kapital and a group of business angels. Link
• PathXl, a provider of web-based workflow solutions for digital pathology has been acquired by Philips. Link
• iLab Solutions, a provider of cloud based laboratory management software has been acquired by Agilent Technologies. Link
• Shyft Analytics, a cloud data and analytics platform for the global life sciences industry, has raised $12.5 million in series B funding round from McKesson Ventures, Medidata Solutions, Health Enterprise Partners and Milestone Venture Partners.Link

SOME INTERESTING STARTUPS FOUND

Phosphorus (2016, New York) – A computational genomics company providing diagnostic tools for clinicians and researchers.
Invio (2016, Seattle) – Offers data monitoring and source data verification for clinical trials.
Jungla (2016, San Francisco) – Offers solutions for modeling of genetic variants and finding correlation with disease states using advanced statistical modelling.

LEADER BOARD – LIFE SCIENCE – SOFTWARE

Bioinformatics
Metabolon (2000, Durham, $77.42M) provides platforms and informatics systems for biomarker discoveries and diagnostic tests and also offers metabolomics research services. Backed by Aurora Funds, Sevin Rosen Funds, Camden Partners Holdings, Essex Woodlands, HHVC, Sumitomo Corp, Syngenta, Alexandria Real Estate Equities, ATEL Capital Group, Fletcher Spaght, The Trelys Funds, Fulcrum Financial Group, and Crossroads Capital.
Simulations Plus (1996, Lancaster, Public) develops absorption, distribution, metabolism, excretion, and toxicity (ADMET) modeling & simulation software for cheminformatics and drug discovery and provides consulting services.
Inpharmatica (1998, Saffron Walden, $75M, Acq) offers predictive informatics solutions and services for medicinal chemistry and ADME to help improve the speed and productivity of drug discovery. It is also involved in research of drugs and biomarkers. Backed by Vertex Ventures, Advent Venture Partners, Gimv, Gilde, 3i Group, Abingworth, Unibio, and REV. Acquired by Galapagos in Dec 2006.
Schrodinger (1990, New York, $52M) develops software solutions for computational chemistry, research and drug discovery. Backed by Cascade Investment.

Imaging Solutions
Aperio Technologies (1999, California, $47.6M, Acq) offers digital pathology solutions including image management, sharing and analysis solutions. Backed by BlackRock, Advanced Technology Ventures, HLM Venture Partners, and Galen Partners. Acquired by Leica Microsystems in Aug 2012.
Parexel (1983, Massachusetts, Public) is a clinical research organization which offers clinical trial management solutions and services. Backed by Capvis.
inviCRO (2008, Boston, $45.8M) provides advanced data analysis services and software in the field of preclinical imaging research.
Media Technologies (2002, Valbonne, $53.66M, Public) offers medical imaging software and services for oncology clinical trials, cancer screening, and clinical practice. Backed by NEA, Draper Fisher Jurvetson, Auriga Partners, Abingworth, Omega Funds, Idinvest Partners, National Technology Enterprises Company, Kuwait Life Sciences Company (KLSC), and AGF Private Equity.

Clinical Trial Solutions
Medidata (1999, New York, $66.18 M, Public) provides cloud based solutions for clinical trial management and analytics. Backed by Insight Venture Partners, Milestone Venture Partners, Stonehenge Growth Equity, Silicon Alley Venture Partners, The Lambda Funds, State Street, and Alpha Venture Partners and went public in June, 2009.
Parexel (1983, Massachusetts, Public) is a clinical research organization which offers clinical trial management solutions and services. Backed by Capvis.
Datatrak International (1991, Cleveland, Public) offers clinical enterprise solutions which include tools for electronic data capture, trial design, trial supply management and project management.
OmniComm Systems (1997, Lauderdale, Public) provides web-based electronic data capture (EDC) and eClinical (eClinical) software and services for clinical research.
Comprehend (2010, Palo Alto, $30.8M) provides clinical data reporting and  visualization tools for clinical trials. Backed by Y Combinator, Lightspeed Venture Partners, Sequoia Capital, SV Angel, Menlo Ventures, Crosslink Capital, Quotidian Ventures, Ulu Ventures, Life Sciences Angel Network, and Easton Capital.

GRC Solutions
Metric Stream (1999, Palo Alto, $123M) provides solutions for quality management, regulatory compliance, risk management, and corporate governance. Backed by Goldman Sachs, KPCB, Integral Capital Partners, Gold Hill Capital, Sageview Capital, Saints Capital, Kaiser Permanente Ventures, Blade Ventures, Montage Capital, and The Camelot Group.
Virtify (2004, Lexington, $23.5M) provides enterprise content and compliance management solutions for the life sciences industry. Backed by Tudor Growth Equity, Blue Cloud Ventures, and Spring Lake Equity Partners.
Qumas (1994, Cork, $10M, Acq) provides Compliance and Quality Management Software for Life Sciences including solutions for document management, process management and submission management. Backed by  General Catalyst Partners, Fidelity Ventures, Delta Partners, ACT Venture Capital, Fidelity Growth Partners Europe, Kernel Capital, and Eight Roads Ventures. Acquired by Accelrys in Dec, 2013.

Workflow Automation Solutions
Emerald Therapeutics (2010, San Francisco, $34M) has developed Emerald Cloud Laboratory that scientists can remotely access via the internet and can perform experiments using automated robotics. Backed by Founders Fund, Western Technology Investment, and Schooner Capital.
Quartzy (2009, Palo Alto, $28.8M) offers web-based platform for lab management and supports collaboration, inventory and order management. It also hosts catalogs from vendors for lab consumables. Backed by  Y Combinator, Lerer Hippeau Ventures, SV Angel, Khosla Ventures, Washington U., Silicon Badia, Reinmkr Satsang, A Capital, Life Science Angels, Science House, Accelerator Tech, Lerer Hippeau Ventures, and Eminence Capital.

Business Intelligence
IMS Health (1954, Danbury, Public) offers a suite of market intelligence products and services which are aimed at improving productivity and healthcare delivery of healthcare organizations.
Humedica ( 2008, Boston, $63M, Acq) offers clinical intelligence and analytics solutions. Backed by  Bain Capital Ventures, General Catalyst Partners, North Bridge Venture Partners, Bain Capital, Leerink Partners, and Flare Capital Partners. Acquired by Optum Health in Jan, 2013.
Zephyr Health (2011, San Francisco, $33.5 M) offers Zephyr Illuminate, an Insights-as-a-Service platform designed to help companies improve product life cycle performance with customer and market insights and can be used for collaboration, targeting and segmentation, and planning. Backed by KPCB, Jafco Ventures, and Icon Ventures.

Sales and Marketing
Veeva Systems (2007, San Francisco, $ 4 M, Public) offers Content Management, Customer Relationship Management, Customer Master data management and related software and services to the life sciences industry. Backed by  Lead Edge Capital, and Emergence Capital. Went public in October 2013.
Aktana (2008, San Francisco, $25 M) offers sales force solutions and customer relationship management solutions for life sciences industry. Backed by Safeguard Scientifics, and Starfish Ventures.

Operations Management and Supply Chain
Tracelink (2009, Woburn, $25.5 M) offers an online platform for global distribution, visibility and traceability of pharmaceuticals to limit the sale of counterfeit drugs. Backed by FirstMark Capital, Volition Capital, and F-Prime Capital Partners.
Bluechiip (2003, Scoresby, Public) provides wireless tracking solutions for bio samples and other products. Went public in Oct, 2010 via a reverse takeover by Sofcom Limited.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates, visit Life Sciences – Software feed.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – DIAGNOSTICS

• Myriad Genetics to acquire pharmacogenomics specialist Assurex Health for $410M. Link
• Debiopharm Group invests ‘tens of millions of dollars’ in Canadian Dx company GenePOC. Link
  
• Consumer genetics company Color Genomics raises $38.5M round. Link
• Mitra Biotech closes $27.4M Series B round, led by Sequoia India and Sands Venture Capital Link
• Singlera Genomics raises $20M in Series A financing led by Lilly Asia Venture. Link
• Avelas Biosciences, maker of fluorescent molecular imaging tools, completes $20M Series C round. Link
• Metabolon raises $15M round to finance precision medicine tests. Link
• Gobiquity raises $6M in first close of Series B round for its smartphone app to detect ambylopia in kids. Link
• BBB Technologies closes $5M Series A round for its Android-based mobile testing device. Link
• UPMC leads a $5M investment round for Cernostics, developer of the TissueCypher™ platform. Link
• Biomerieux to collaborate with Jackson Labs for the development of infectious disease diagnostics. Link

SOME INTERESTING STARTUPS FOUND

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – MEDICAL DEVICES

• FDA approves Intuity Elite rapid valve from Edwards Lifesciences which has already received CE Mark approval in April 2014. Link
• FDA approved an expanded indication for the Sapien XT and Sapien 3 replacement heart valves (from Edwards Lifesciences) for intermediate-risk patients. Link
• Bluegrass Vascular Technologies received CE Mark approval for its Surfacer vascular access device. Link
• BiO2 Medical received FDA 510(k) clearance for its Angel Catheter designed for pulmonary embolism protection. Link
• Bonesupport won an investigational device exemption for the Fortify clinical trial of its G injectable antibiotic-eluting bone substitute which has already won CE Mark approval in 2013. Link
• Johnson & Johnson subsidiary Biosense Webster won FDA premarket approval for its Thermocool SmartTouch SF catheter designed for ablation procedures. Link
• Fortimedix Surgical received FDA 510(k) clearance for its FMX314 single-port system for minimally invasive abdominal laparoscopic surgery. Link
• Siemens received FDA 510(k) clearance for its Somatom Drive computed tomography dual-source scanner. Link
• FDA has cleared two of Stryker’s clot retrieval devices as a first-line therapy for ischemic strokes to be given alongside a clot-dissolving drug. Link
• Medtronic has received FDA approval for the Enlite sensor with iPro2 Professional Continuous Glucose Monitoring (CGM) system Link
• Allergan acquires drug-eluting ophthalmological implant maker ForSight Vision5 for $95M. Link
  
• Globus Medical acquired Alphatec’ international operations and distribution channels for $80M. Link
• Avelas Biosciences, a developer of imaging molecules for detection and diagnosis of cancer tumors, raised $20M in a Series C round led by Pharmstandard International. Link
• ViewRay, a developer of MRI-guided radiation therapy technology for cancer, riased $14M in private placement from OrbiMed Advisors, Xeraya Capital and Kearny Venture Partners. Link

SOME INTERESTING STARTUPS FOUND

RetiSpec (2015, Tel Aviv) – Develops non-invasive eye scanner for early detection of Alzheimer’s Disease.
Augmedics (2014, Yokneam Illit) – Develops Augmented Reality Guided Surgery System.

LEADER BOARD – MEDICAL DEVICES

THERAPEUTICS

Cardiovascular
TriVascular (1998, Santa Rosa, IPO) – Medical devices for endovascular aortic repair. Went public in 2014.
CVRx (2001, Minneapolis, $390M) – Implantable technology for hypertension and heart failure. Backed by DaVita Healthcare Partners, Piper Jaffray, Ysios Capital, JJDC, InterWest Partners, Silicon Valley Bank, SightLine Partners, NEA, Kearny Venture Partners, Frazier Healthcare Partners, ABS Ventures.

Orthopedics
ConforMIS (2004, Bedford, IPO) – Personalized, partial knee resurfacing implants to treat knee osteoarthritis. Went public in 2015.
Small Bone Innovations (2009, Morrisville, $171M) – Suite of orthopedic products for small bones and joints. Backed by Trevi Health Ventures, Goldman Sachs, Malaysian Life Sciences Capital Fund, NGN Capital, Viscogliosi Brothers, Axiom Ventures, Khazanah Nasional Berhad, 3i Group.

Surgery
Auris Surgical Robots (2009, San Carlos, $184M) – Robotic microsurgical systems for ophthalmic surgery. Backed by NaviMed Capital, Lux Capital, Mithril Capital Management and Highland Capital Partners.
Medrobotics (2011, Raynham, $140M) – Robotic surgical devices for minimally invasive surgery. Backed by Hercules Technology Growth Capital and Pittsburgh Life Sciences Greenhouse.

Ophthalmology
TearScience (2005, Morrisville, $151M) – Diagnosis and Treatment of Evaporative Dry Eye. Backed by Spray Venture Partners, Essex Woodlands Health Ventures, HealthCare Royalty Partners, Investor Growth Capital, DeNovo Ventures and Quaker BioVentures.
Avedro (2007, Waltham, $130M) – Corneal cross-linking technology. Backed by Interwest, OrbiMed Advisors, Prism Venture Management, DeNovo Ventures, Flagship Ventures, Aperture Venture Partners, SCP Vitalife Partners, Borealis Ventures, Abingworth, Third Point, and Prism Venture.

DIAGNOSTICSPlatform Technologies
Neusoft Medical System (1998, Shenyang, $410M) – Medical imaging device and software developer. Backed by China Everbright Group AG, Goldman Sachs, Hony Capital.
Butterfly Network (2011, Guilford, $100M) – Medical imaging devices using a combination of deep learning and an ultrasonic device. Backed by Aeris Capital.

Oncology
Veran Medical (2005, St.Louis, $83M) – Soft tissue navigation for diagnosis of lung cancer. Backed by Prolog Ventures, Versant Ventures, River Cities Capital Funds, Advantage Capital Partners, Rex Health Ventures, 3G Capital Partners and Vectis.
SuperDimension (1995, Minneapolis, $63M) – Electromagnetic navigation bronchoscopy to diagnose and treat cancer. Backed by Orbimed, Pitango Venture Capital, Saints Capital, Oxford Bioscience Partners, Oxford Capital, Pfizer, Covidien, CIBC Equity Research, Medica Venture Partners and Tivona Capital.

Infectious Disease
Accelerate Diagnostics (2004, Tucson, IPO) – In vitro diagnostics to provide solutions for the antibiotic resistant infections. Went public in 2013.
Curetis (2007, Holzgerlingen, $85M) – Molecular diagnostics POC device for infectious diseases. Backed by Forbion, KfW Bankengruppe, HBM Partners, BioMedPartners, CD-Venture GmbH, Roche, Qiagen, Life Sciences Partners, Aeris Capital.

MONITORING Diabetes
OptiScan Biomedical (1994, Hayward, $156M) – Glucose monitoring systems for ICUs/CCUs. Backed by yet2Ventures, Mitsui, Medven, Lightstone Ventures, Oakwood Medical, Ascension Ventures, NGN Capital, Signet Healthcare Partners, Mitsui, Hercules Technology Growth Capital, Prism Venture, EGS Healthcare Capital Partners, Morgenthaler.
Senseonics (1996, Germantown, $124M) – Implantable system for continuous glucose monitoring. Backed by NEA, HealthCare Ventures, Rho Capital Partners, Anthem Capital Management, Delphi Ventures and Greenspring Associates.

Cardiovascular
CardioMEMS (2001, Atlanta, $153M, Acq.) – Wireless sensor-based implants for cardiac monitoring. Acquired by St. Jude Medical in 2014.
iRhythm Technologies (2006, SF, $95M) – Cardiac rhythm monitoring devices. Backed by Mohr Davidow Ventures, Synergy Life Science Partner, Novo A/S, Norwest Venture Partners, California HealthCare Foundation, Stanford University, Kaiser Permanente Ventures, New Leaf Venture Partners and New Leaf Ventures.

Vital Signs
EarlySense (2004, Ramat Gan, $85M) – Contact free patient monitoring solution. Backed by Noaber, Bridge Investment Fund, Samsung Venture Investment Corporation, Docor, ProSeed, Pitango VC, Israel, Mitsui & Co, JK&B Capital, Bank Hapoalim, Welch Allyn, Challenge.
Sotera Wireless (2004, San Diego, $68M) – In hospital patient monitoring device. Backed by Sanderling Ventures, Qualcomm Ventures, Intel Capital, EDB Investments, Safeguard, Delphi Ventures, Cerner Capital, West Health and Sanderling.

CLINICAL EQUIPMENT
TransMedics (1998, Andover, $264M) – Organ transplantation technology. Backed by Tudor Funds, Abrams Capital, Flagship Ventures, Kleiner Perkins, Foundation Capital, Sagamore, Hercules Technology Growth Capital, Alta Partners, Sherbrooke Capital, VantagePoint Capital Partners and i Group plc.
Caesarea Medical Electronics (1993, Caesarea, $100M) – Infusion and syringe pump systems and accessories. Backed by CareFusion.

SUPPORT SYSTEMS
Ekso Bionics (2005, Richmond, IPO) – Bionic exoskeleton for people with paralysis. Went public in 2014.
BionX Medical (2007, Bedford, $75M) – Prosthetic device to aid movement of lower-limb amputees. Backed by Sigma Partners, General Catalyst, WFD Ventures and Gilde Healthcare.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates, visit the Medical Devices feed.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – HEALTHCARE ANALYTICS

• Cohealo, an online platform provider for peer-to-peer medical equipment sharing between hospitals, received $2M Series A funding led by Romulus Capital, Krillion Ventures, Struck Capital, and various angel investors. Link
• Nanotech Galaxy, a provider of a computer-aided tool for radiologists to diagnose images, raised $20K Seed funding. Link
  
• NextHealth Technologies, a prescriptive analytics and consumer engagement platform, raised $8.5M Series A funding led by Norwest Venture Partners. Link
• Advenio TechnoSys, a provider of software solutions for computer-aided diagnostics, raised $100K Seed financing from KStart, the seed programme of venture capital firm Kalaari Capital. Link 
• DoseMe, a provider of a drug dosage tool for clinicians, received $2.6M Series A funding from Greg Spurgin and Gary Cunningham. Link

SOME INTERESTING STARTUPS FOUND

Torq Labs (2016, Milwaukee) – Provides an intelligent motion analytics for the modern athletes’ treatment and injury prevention.
InnovationDx (2016, St. Louis) – Offers machine learning and deep learning algorithms for diagnosing medical images for healthcare organisations.
WoundMetrics (2016, Scottsdale) – Provider of precision wound care tool for medical professionals to avoid hospital infections.

LEADER BOARD – HEALTHCARE ANALYTICS

Suite Solutions
Inovalon (1998, Bowie, IPO) – Cloud-based analytics platform for clinical, financial and quality insights. Went public in 2015.
Evolent Health (2011, Arlington, IPO) – An integrated platform for population health, financial and operational analytics. Went public in 2015.
Flatiron Health (2012, NYC, $314M) – Cloud-based Cancer care platform for clinical, financial and operational intelligence. Backed by Google Ventures, Roche, First Round Capital, Social Capital, SV Angels and more.
Health Catalyst (2008, Salt Lake City, $237M) – A suite of health analytics and data management solutions to help identify care gaps and support process improvement. Backed by Sequoia Capital, Norwest Venture Partners, Sands Capital Ventures, Sorenson Capital and more.

Clinical Analytics
Proteus Digital Health (2001, Redwood City, $404M) – Medication adherence platform using sensor-enabled pills, biometric sensor patch and data analytics. Backed by Novartis, Medtronic, Oracle, KP Ventures.
Imaging Advantage (2007, Santa Monica, $295M) – Cloud-based clinical decision support tool for radiologists. Backed by Goldman Sachs, Brightwood Capital Advisors and CRG.
Heart Flow (2007, Redwood City, $227M) – Non-invasive decision support tool for diagnosing blood flow blockages in the heart. Backed by Capricorn Investment Group and more.
Welltok (2009, Denver, $151.5M) – PaaS based analytics platform for health optimization and population health management. Backed by Qualcomm Ventures, EMCAP partners, Interwest Partners, Bessemar Venture Capital.

Financial Analytics
MediGain (2002, Plano, $46M) – Analytics tools for revenue cycle management, billing and reimbursement. Backed by Prudential Capital Partners.
Apixio (2009, San Mateo, $42M) – Cognitive computing platform for risk adjustment coding. Backed by SSM Partners, First Analysis and Bain Capital Ventures.
Truveris (2009, NYC, $27M) – SaaS-based platform for prescription claims analytics and pharmacy data validation. Backed by New Leaf Venture Partners,Tribeca Venture Partners, First Round, New Atlantic Ventures and more.
LaunchPoint (2008, Rolling Meadows, $26M) – Cloud-based healthcare analytics platform for payment integrity solutions. Backed by Carrick Capital Partners.

Operational Analytics
Evariant (2008, Farmington, $68.5M) – CRM analytics platform for digital marketing and patient engagement. Backed by Goldman Sachs, Lightspeed Venture Partners, Health Enterprise Partners, Dignity Health and Salesforce Ventures.
Kyruus (2010, Boston, $56M) – Referral management solutions using analytics and data mining. Backed by Venrock, Mckesson Ventures, New Leaf Venture Partners, Highland Capital Partners and more.
OnShift (2008, Cleveland, $30M) – SaaS based staff scheduling software that predicts and prevents overtime and under-staffing. Backed by Health Velocity Capital, HLM Venture Partners, Draper Triangle, West Capital Advisors and more.
PatientPop (2014, Santa Monica, $24M) – End-to-end marketing platform that uses analytics for performance measurement. Backed by Toba Capital, Athena Health and Silicon Valley Bank.
Binary Fountain (2003, Mclean, $22M) – Cloud-based platform for analyzing patient feedback from social media, surveys and online sites. Backed by HLM Venture Partners, Pioneer Venture Partners and Providence Health & Services.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates, visit the Healthcare Analytics feed.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – HEALTHCARE IT

• Casetabs, a surgery care coordination app for healthcare organizations raised a funding of $2.6M in Series A from Evolution Financial Group. Link
• Next Health Technologies,a health care analytics SaaS platform and services provider that offers to recommend, manage and optimize consumer engagement raised a funding of $8.5M in Series A led by Norwest Venture Partners, with participation from existing investors. Link
• NextGxDx, an online genetic testing marketplace that offers healthcare professionals and hospitals the ability to access up-to-date listings of all genetic tests raised a funding of $1.47M in Series B. Link
• OneMedNet, a platform for secure, on-demand exchange of medical images raised a funding of $900K in Series A. Link
• ClearCare, a SaaS software for private-duty home care agencies raised a funding og $60M in Series C led by global investment firm Battery Ventures. Link
• Gliimpse, provides a technology which turns medical documents into data was acquired by Apple for an undisclosed amount. Link
• DoseMe, is a software that allows clinicians to dose a patient based on that patient’s individual ability to absorb, process, and clear a drug raised a funding of $2.6M in Series A from Greg Spurgin and Gary Cunningham, founders of US company Results Physiotherapy. Link
• Mint Solutions a tech based platform to verify medications, prevent errors, and educate patients raised a funding of $5.6M in series B led by Brabant Development Agency (BOM Capital) and existing shareholders LSP (Life Sciences Partners). Link
• Gobiquity, Provides mobile applications for the early detection and tracking of eye diseases raised a funding of $6M in Series B from Interwest Partners. Link
• Allcure, specializes in cloud-based clinical decision support to improve tumour diagnosis, treatment level and survival rate of patients raised a funding of $27M in Series A. Link
• Patient IO, an enterprise platform that transforms paper-based care plans into mobile solutions was acquired by Athena Health. Link
• Zillion HIPAA compliant cloud based PaaS platform for healthcare providers to drive patient engagement raised a funding of $2.8M in Series C from Twins Focus Capital. Link
• Precedent Health, offers managed care expertise to help healthcare providers navigate through upcoming industry challenges and opportunities raised a funding of $2M in Series B from Claritas Capital. Link
• Cohealo, an asset mobilization and analytics platform for the healthcare industry raised a funding of $2M in Series A led by Romulus Capital. Link
• Chrono Therapeutics, a wearable – wrist, arm, or as an adhesive patch, that helps a user in smoking cessation raised a funding of $47.6M in Series B. Kaiser Permanente Ventures led the round with participation from other investors that included Endeavour Vision, Xeraya Capital, Labuan Ltd, Emergent Medical Partners, Canaan Partners, 5AM Ventures, Fountain Healthcare Partners, GE Ventures, Hikma Ventures, Cota Capital and Mission Bay Capital. Link
• Glooko, a provider of health and wellness solutions for employers and members raised a funding of $8M led by venture capital firm Canaan Partners and joined by Social Capital, Samsung Ventures and Glooko founder Yogen Dalal. Link
• Diabetes device developers Glooko and Diasend merge to Deliver the World’s Premier Diabetes Management Platform. Link
• Big Cloud Analytics, a provider of real time predictive analytics technology focussed on IOT data from wearable and other medical devices raised a funding of $4.5M in Series A from Edison Partners. Link
• DICOM Grid which has rebranded itself into Ambra Health, is a cloud based platform for medical image management and exchange. raised a funding of $6M led by Cannan Partners. Link
• Klara, a Healthcare messaging company raised a seed funding of $3M. Link
• Eventide Asset Management buys $24,997,088 stake in athenahealth Inc (ATHN). Link
• Deerfield Management Co buys $56,501,680 stake in Healthways (HWAY). Link

SOME INTERESTING STARTUPS FOUND

Algosurg (2016, Mumbai) – Offers Tabplan, a 3D surgery planning software using 2D X-ray image.
Snapcare (2016, Delhi) – Provides a personalized healthcare assistant which allows doctors to create diagnoses and personalized treatment plans
Scribe.AI (2016, Seattle) – It listens the physician-patient interactions and brings up the right clinical information at the right time
CareCDS (2016, Detroit) – Offers a clinical decision support software for healthcare providers.

LEADER BOARD –  HEALTHCARE IT

VALUE BASED CARE
Evolent Health (2011, Virginia, IPO) – Provides healthcare technologies and services that improve clinical, operational and business outcomes. The company’s services include providing customers with a population. Went public in 2015.
Privia Health (2007, Virginia, $419M) – Builds and enables physician groups and clinically integrated provider networks using technology, team-based care, and wellness programs to help doctors to manage the health of their populations. Backed by Goldman Sachs, Pamplona Funds, Cardinal Partners, Brighton Health, Health Enterprise Partners and Morgan Noble.
Lumeris (2001, Maryland Heights, $211M) – Provider of population health management solutions to health systems, payers and providers. Backed by BlueCross BlueShield Venture Partners, Camden Partners, Kleiner Perkins Caufield & Byers and Sandbox industries.

Population Health Management
MedHOK (2009, Tampa, $77M) – Provides a SaaS-based platform that uses predictive analytics to allow payers to identify and target member health risks, trigger workflow interventions, and improve the quality of care. Backed by Spectrum Equity and Bain Capital Ventures.
Humedica (2008, Boston, $63M, Acq) – Provides analytics solutions for healthcare providers to create a longitudinal view of individual patients and patient populations by gathering, normalizing, and analyzing data from EHRs, practice management, claims data. Backed by NorthBridge and Bain Capital Ventures.

Patient Engagement
Accolade (2007, Pennsylvania, $163.5M) – Provides consumer healthcare engagement and influence solution for large self-insured employers and payer organizations. Backed by Mckesson, Carrick Capital Partners, Com Cast Ventures.
MindMaze (2012, Lausanne, $118.5M) – Develops interfaces for neuro-rehabilitation, game training, and 3D imaging, using VR/AR and neurophysiological recording technologies.

Medication Adherence
Proteus Digital Health (2001, California, $404M) – Digital medicine platform includes unique measurement tools like sensor enabled pills, a biometric sensor patch worn on the body that receives data from sensors and sends it to the cloud, from where it can be analyzed using a smartphone app by doctors and caregivers. Backed by Novartis, Medtronic, Oracle, KP Ventures.

Care Coordination
Remedy Partners (2006, SF, $95M) – Enables healthcare providers in developing and operating patient-centric episodic payment programs. Backed by Bain Capital ventures.
PatientSafe Solutions (2002, San Diego, $88.5M) – Provides smart point-of-care mobile solutions and innovating technologies enabling accountable care for healthcare organizations. Its flagship product, the PatientTouch System, delivers measurable safety and quality improvement by making care team workflows streamlined.

Remote Monitoring
LifeWatch (1993, New Jersey, IPO) – It is a maker of a medical device to be are worn on the chest to record heart’s rhythm. The data is continuously collected and analyzed in a dedicated mobile device.
iRhythm Tech (2006, SF, $95M) – Its product the Zio Patch is a wearable patch designed to gather beat-to-beat heart data for diagnosis of cardiac arrhythmias. Backed by California Healthcare Foundation, Kaiser Permanente Ventures, Mohr Davidow Ventures, New Leaf Venture Partners, Northwest Venture Partners, and Synergy Life Science Partners.
EarlySense (2004, Tel Aviv, $85M) – Developed a sensor that is placed under the mattress and monitors body vitals as well as bed entries and exits, patient motion, and quality of sleep eliminating the need for regularly manually checking the patients in constant care. Backed by Pitango Capital Ventures and JKB Capital.
AirStrip technologies (2003, San Antonio, $65M) – Platform allows clinicians to securely access patient monitoring data such as continuous heart tracings and other waveforms – along with parameters such as BP, temperature, etc from EMRs, bedside monitors, and devices on their laptops and mobiles. Backed by Sequoia Capital, Welltrust Fund,and Qualcomm Ventures.

Suite Solutions
Epic (1979, Madison) – Develops, implements and supports IT software solutions for healthcare providers.
Cerner (1979, Kansas City, IPO) – End-to-end healthcare information technology solutions and services for the healthcare provider to optimize clinical, financial and operational outcomes.Went public in 1986.

EHR Platform
Practice Fusion (2005, SF, $155M) – Provides a free, web-based Electronic Health Record (EHR) platform to physicians. Backed by Qualcomm, Longitude Capital, Artis Ventures, SV Angels, Band Angels, Orbimed and KPCB
Kareo (2004, Irvine, $137M) – Provides a SaaS-based practice management system to healthcare providers. Backed by  Escalate Capital, OpenView, SVB Financial Group, Montreux Equity Partners, Silver Lake, Greenspring Associates, Western Technology Investment, Stripes Group.

Practice Management
We Doctor Group (2010, Hangzhou, $521M) – We Doctor Group, earlier Guahao offers a platform to consumers and doctors, to book and manage appointments. Offers a practice management solutions to healthcare providers. Backed by Tencent, Fosun, Morningside Ventures, Qiming Ventures and Shandong Tyan Home Co.
Practo (2008, Bangalore, $125M) – Offers a web-based platform to patients and doctors. The SaaS-based practice management solution for physicians is called Practo Ray. Backed by Matrix Partners, Sequoia Capital, Tencent, Google Capital and InnoVen Capital.

Home care Management
Homecare Homebase (2001, Dallas, $57M) – Cloud-based tech enabler for Hospice & HomeCare organizations. Backed by SV Life Sciences.
Kinnser Software (2003, Austin, $40M) – Offers web-based software solution for point of care, billing and administration services to home health agencies. Backed by Insight Partners and Georgian Partners.

Clinical Operations Management
Imaging Advantage (2007, Santa Monica, $295M) – Offers RadAdvisor, a cloud-based decision support platform for radiologists that helps in diagnostic decision support. Backed by Goldman Sachs, Brightwood Capital Advisors, and CRG.
HeartFlow (2007, Redwood City, $227M) – Provides cardiovascular diagnostic support using CT scans and high-performance computing to provide physicians with data about blood flow within the coronary arteries. Backed by Capricorn Investment Group and US Venture Partners.

Administrative Solutions
Livescribe (2007, Oakland, $156M, Acq) – Provides smart CPOE solution platform for healthcare providers. Backed by Qualcomm, Greenhouse Capital Partners, Scale Venture Partners, Double Bottom Line Investors, Lionhart, TransLink Capital, Keating Capital, Presidio Ventures, Crosslink Capital, DBL Partners, Aeris Capital, VantagePoint Capital Partners. Acquired by Anoto in Nov 2015.
Awarepoint (2002, San Diego, $88M) – Offers Location-as-a-Service for healthcare organizations to facilitate asset management and tracking. Backed by KPCB, Cardinal Partners, SVB Financial Group, Venrock, Heritage Group, Icon Ventures Jafco Ventures, Avalon Ventures, Avalon Ventures, Top Tier Capital Partners, New Leaf Ventures.
Phreesia (2005, NYC, $76M) – Provides a patient check-in platform for healthcare providers. Backed by BlueCross BlueShield Venture Partners, Escalate Capital, Ascension Ventures, Ascension Ventures, LLR Partners, Polaris Partners, Sandbox Industries, Long River Ventures, HLM Venture Partners, VantagePoint Capital Partners.
Evariant (2008, Farmington, $69M) – Provides platform for digital marketing solutions. Backed by Lightspeed Venture Partners, Health Enterprise Partners, Enterprise Partners Venture Capital and Goldman Sachs.

Professional Networks
Doximity (2011, San Mateo, $82M) – Mobile/web networking platform for physicians, medical professionals. Backed by Interwest Partners, Emergence Capital, T. Rowe Price, DFJ Venture, Morgan Stanley and Morgenthaler Private Equity.
Sermo (2000, New York City, $60M) – Social network for physicians. Backed by Kennet Partners and Deerfield Capital Management.

Horizontal
McKesson (1833, SF, IPO) – Provides solutions that include pharmaceutical and medical-surgical supply management, healthcare information technology, and business and clinical services. Went public in 1994.
Imprivata (2002, Tennesse, IPO) – Provides secure access and collaboration solutions for enterprises. It strengthens user authentication, streamlines application access and simplifies compliance reporting across multiple computing environments. Went public in 2014.
MedSolutions (2002, Tennesse, IPO) – Provides Intelligent Cost Management, that encompasses utilization management, capturing savings, reducing treatment costs, and supporting diagnostic accuracy.
Health Catalyst (2000, Utah, $237M) – Provides multiple analytical products, services, and applications like population health management, patient injury prevention, operational efficiency, performance monitoring and financial management for healthcare organizations. Backed by Sequoia Capital, Kp Ventures, Epic Venture Capital, Sorenson Capital.

EMPLOYER
Benefits Administration
Castlighthealth (2008, SF, IPO) – Offers healthcare information on providers and pricing for enterprises. Went public in 2014. Went public in 2015.
Collective Health (2013, San Mateo, $119M) – Self-insurance SaaS platform for employers to sponsor their employees. Backed by Google Ventures, Rock Health, Redpoint Ventures, Maverick Capital, New Enterprise Associates, Founders Fund and RRE Ventures.

Employee Fitness & Wellness
Welltok (2009, Denver, $151M) – Platform which provides personalized incentive based patient engagement services for Population health managers. Backed by Bessemer Venture Partners, Emergence Capital Partners, InterWest Partners, New Enterprise Associates (NEA), Qualcomm Ventures, Miramar Digital Ventures, Okapi Venture Capital, Georgian Partners, EDBI and Flare Capital Partners.
Virginpulse (2004, Framingham, $92M) – Provides hub of tools that foster employee engagement and wellness.Backed by Insight Venture Partners and Virgin Group.

Healthcare Delivery
Imaginehealth (2006, Midvale, $36M) – Provider of customize fleet of Healthcare providers to employers. Backed by HLM Venture Partners and Trident Capital.
Healthiestyou (2010, Scottsdale, $30M) – Teleconsultation service provider for employees. Backed by Frontier Capital.

PAYER
Connecture (1997, Brookfield, IPO) – Web-based health plan distribution platform for healthcare payers. Went public in 2014.
NexgenRx (2003, Toronto, IPO) – Web-based claims adjudication and benefits administration for processing prescription drugs, and dental office claims. Went public in 2006.
ikaSystems (1999, Southborough, $152.5M, Acq.) – Software suite for health plans that includes claims submission and authorization, member and provider portals, electronic billing and claims adjudication solutions. Backed by Essex Woodlands Health Ventures. Acquired by Blue Cross Blue Shields in 2015.
HealthEdge (2004, Burlington, $58M) – Suite of software products for the healthcare payer market that includes claims and benefits administration, care management, business intelligence and portal solutions. Backed by Psilos.

PHARMACY
Express Scripts (1986,Missouri, IPO) – Offers SaaS platform of pharmacy benefit management solutions for health plans, providers, and patients.
CatamaranRx (1981,Illinois, Acq) – Provides pharmacy benefit management solutions and connect pharmacists, doctors and caregivers with prescription data to improve health outcomes.
Talyst (2012,Washington, $65M) – Pharmacy Management solutions to pharmacies. Backed by OVP Ventures, Align Investments, Ignition Partners
MedAvail (2012,Ontario, $36M) – Offers a self-service kiosk solution called the MedAvail MedCenter, automating the dispensing of prescription drugs and Over-The-Counter medications. Backed by Walgreens, Redmile Group, Adage Capital.
Millennium Pharmacy Systems (2003, Oakbrook, $62M) – Offers Just-In-Time dispensing with e-prescription, administration, documentation, and reporting. Backed by Essex Woodlands, Boulder Ventures, ATEL Capital Group, CHL Medical Partners, Ascension Ventures, and HealthInvest Equity Partners.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates, visit Healthcare IT feed.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – BIOPHARMA

• Gene editing startup CRISPR Therapeutics files for $90M IPO. Link
• AC Immune lines up a $68M IPO on NASDAQ for the development of liposomal therapeutic vaccines. Link
• Dermatology biotech Novan goes for $60M IPO. Link
• Oral pain specialist Thar Pharmaceuticals files for a $50M IPO. Link
• Moderna enters new growth phase with the closing of $474M equity financing and its first BARDA grant for up to $125M for Zika mRNA vaccine. Link
• Denali snags $130M, deals in quest to summit Alzheimer’s, ALS, Parkinson’s. Link
• Arcus Biosciences emerges from stealth mode with $120M in financing and an approach for personalized immunotherapy. Link
• Third Rock backed Relay Therapeutics launches with a $57M Series A for its protein motion platform. Link
• Peloton Therapeutics raises $52.4M Series D for its renal cell carcinoma drug. Link
• Proclara gets $47M to target protein misfolding in Alzheimer’s and beyond. Link
• Delinia raises $35M Series A round from Sofinnova Partners and Atlas Ventures for autoimmune R&D. Link
• Allergan acquires autoimmune company Vitae Pharmaceuticals for $639M cash. Link
• Allergan acquires gene therapy company RetroSense Therapeutics for $60M, adding optogenetics technology to company’s eye care pipeline. Link
• Pfizer signs an $250M deal with OncoImmune for its CTLA4 antibody. Link
• Bayer and CRISPR Therapeutics $335M gene editing joint venture, named Casebia Therapeutics. Link

SOME INTERESTING STARTUPS FOUND

LEADER BOARD – BIOPHARMA

Immunotherapy
Juno Therapeutics (2013, Seattle, IPO) – Immunotherapies based on chimeric antigen receptor and T cell receptor technologies to genetically engineer T cells to recognize and kill cancer cells. Backed by Alaska Permanent Fund, ARCH Venture Partners, Venrock & Bezos Expeditions. Went public in 2014.
Stemcentrx (2008, SF, $500M, Acq.) – Antibodies and antibody-drug conjugates (ADCs) to target cancer stem cells. Backed by Founders Fund, Artis Ventures & Fidelity Investments.
Tesaro (2010, Waltham, $366M) – Developing a novel PARP inhibitor (Nilaparib), which is currently in phase III for Ovarian and Breast Cancers. Backed by KPCB, NEA, Interwest, Venrock and others.
Symphogen (2000, Lyngby, $360M) – Recombinant polyclonal antibodies (rpAb) for the treatment of cancer. Lead product, Sym004 being investigated two clinical studies for metastatic colorectal cancer and NSCLC. Backed by Novo, PKA, Danica Pension, Essex Woodlands Health Ventures and others.
CureVac (2000, Tubingen, $350M) – Prophylactic and therapeutic application of messenger RNA (mRNA). Lead programme RNA based immunotherapy for prostate cancer and NSCLC. Backed by Dievini Hopp, Bill & Melinda Gates, Northview Ventures and others.

Infectious Disease
Crucell (1993, Leiden, $443M) – Vaccines for Cholera, Influenza and others. Backed and later acquired by J&J.
Melinta Therapeutics (2000, New Haven, $388M) – Antibiotics for drug resistant antibiotics. Lead Candidate delafloxacin, currently in Phase 3 for acute bacterial skin and skin structure infections (ABSSSI). Backed by Vatera Healthcare Partners, Malin Corporation, Warburg Pincus, ABS Ventures and others.
Chimerix (2002, Durham, $217M) – Dveloping anti-viral therapeutics. Lead candidate (CMX001 – a viral dsDNA inhibitor) has completed phase III and is about to submit the data. Backed by Canaan Partners, Sanderling Ventures, Asset Management Ventures and Frazier Healthcare Partners and others.
Nabriva Therapeutics (2001, Vienna, $193M) – Developing leuromutilin class of antibiotics. Lead product lefamulin has completed Phase II for acute bacterial skin and skin structure infection. Development of alternate formulations for other indications underway. Backed by OrbiMed, Vivo Capital, Novartis Venture Fund, Phase4 Partners and others.

CNS Disease
Alkermes (1987, Dublin, IPO) – Small Molecule therapeutics and drug delivery technologies for multiple Psychiatric diseases. Recently backed in a $250M private equity round of funding from Invesco Perpetual. Went public in 1991
Denali Therapeutics (2015, SF, $347M) – Founded by Ex-Genentech Neuroscience experts with plans to target Neurodegenerative Diseases (Alzheimer’s, Parkinson’s) with targeted therapies based on genetic stratification of patient populations. Raised a record series A from Alaska Permanent Fund, ARCH, Flagship, F-Prime Capital.
ReNeuron Group (1997, Guildford, $216M) – Stem Cell therapies for neurodegenerative diseases. Pre-clinical candidates for Stroke, Parkinson’s, Huuntingon’s, Retinitis Pigmentosa and Diabetes. Backed by Neil Woodford.
TauRx Pharmaceuticals (2002, Singapore, $177M) – Tau Aggregation Inhibitor against Alzheimers and Fronto Temporal Dementia. Lead candidate LMTX in phase 3. Backed by Temasek, DBS, Dundee Corp. and Genting.

Rare Disease
UniQure (Amsterdam, 1998, IPO) – First and currently the only gene therapy product to receive regulatory approval in the European Union (Glybera). Developing other AAV-based gene therapies for Hemophilia and CHF. Backed by Coller Capital, Chiesi Pharmaceuticals, Hercules Technology Growth Capital and BMS. Went public in 2014
PTC Therapeutics (South Plainfield, 1998, IPO) – Small Molecule Drugs for Cystic Fibrosis and Duchenne’s Muscular Dystrophy caused by nonsense mutations. Backed by Bay City Capital, Credit Suisse, Novo A/S, Vulcan Capital, Delphi Ventures, HBM BioVentures and others. Went public in 2013
Chiasma (Jerusalem, 2001, IPO) – Developing oral forms of existing injectible therapies for orphan diseases using their Transient Permeability Enhancer technology. Backed by MPM Capital. Abingworth, ARCH Venture Partners, F2 Ventures and others. Went public in 2015
aTyr Pharma (San Diego, 2005, IPO) – Using physiocrine biology to develop protein therapeutics against rare diseases with an immune component. Lead candidate Resolaris completed Phase Ib/II trail to treat adult facioscapulohumeral muscular dystrophy (FSHD) patients. Backed by Alta Partners, Polaris Partners, Cardinal Partners, Sofinnova Ventures and others. Went public in 2015
Alexion (1992, Zurich, $152M) –  Maker of Soliris, a drug used to treat the rare disorders atypical hemolytic uremic syndrome (aHUS) and paroxysmal nocturnal hemoglobinuria (PNH). 2015 approvals for two Enzyme Replacement Therapies (Strensiq for hypophosphatasia and Kanuma for Lysosomal Acid Lipase Deficiency). Backed by BB Biotech, Pemira, Connecticut Innovations and Invesco Perpetual.

Cardiovascular Disease
Portola Pharma (2003, SF, IPO) – Small molecule therapies for thrombosis, other hematologic disorders and inflammation indications. Backed by Sutter Hill Ventures, MPM Capital, D.E. Shaw & Co., Abingworth, Frazier Healthcare Partners and others. Went public in 2013
Relypsa (2007, Redwood City, IPO) – Non-absorbed polymeric drugs cardiovascular and renal disease. Backed by OrbiMed Advisors, 5AM Ventures, Delphi Ventures, New Leaf Venture Partners and others. Went public in 2013
DalCor Pharma (2015, Montreal, $150M) –  Lead molecule Dalcetrapib (earlier shelved by Roche) is currently in phase III trials for the treatment of a genetic subpopulation of patients suffering from Acute Coronary Syndrome (ACS). Backed by Sanderling Partners, Connecticut Innovations, Fonds de solidarité FTQ and CPDQ                 Cardiorentis (2010, Zug, $119M) – Natriuretic peptides for the treatment of acute heart failure and related cardiovascular diseases. Lead product Ularitide is in Phase III development. Backed by Healthcare Royalty Partners.

Metabolic Disease
Orexigen Therapeutics (2002, La Jolla, IPO) – Maker of Contrave (naltrexone HCl and bupropion HCl extended release) against Obesity. Backed by Morgenthaler, KPCB, Sofinnova Ventures, Domain Associates and others. Went Public in 2007
Intarcia Therapeutics (1997, Boston, $1.13B) – Developing a drug-device combo (exenatide delivered by a subcutaneous osmotic mini-pump) for diabetes. Backed by NEA, Venrock, Silicon Valley Bank, Interwest Partners and many others. 
NGM Biopharmaceuticals (2007, SF, $303M) – Biologics for the treatment of cardio-metabolic diseases & hepatic diseases. Backed by The Column Group, Prospect Venture Partners, Rho Capital Partners and others.
Genfit (1999, Loos, $174M) – Small molecule therapeutics for cardiometabolic and neurodegenerative diseases. Flagship product Elafibranor for NASH is currently in phase 3. Collaborations with Sanofi-Aventis, Solvay group, Servier, and Merck.
Motus Therapeutics (2008, Boston, $125M) – Developing peptide therapeutics for the treatment of gastrointestinal (GI) diseases; and obesity, including obesity caused by genetic deficiencies in the MC4 pathway. Backed by NEA, Orbimed, Third Rock Ventures, Pfizer and others.
Hua Medicine (2010, Shanghai, $125M) – Developing a 4th gen glucokinase (GKA) in-licensed from Roche to treat Type 2 Diabetes. Backed by Venrock, Fidelity Growth Partners, ARCH Venture Partners, Eight Roads Ventures and others. 

Contract Research and Manufacturing
Patheon (2010, Durham, $1.4B, Acq) – Manufacturing prescription and OTC products in solid, semi-solid, liquid, and sterile dosage forms. Offering a range of specialized pharmaceutical development capability, including high-potency, sterile, lyophilization, and controlled-release. Backed by JLL partners and Advent Morro Equity Partners.
Pharmaron (2003, Beijing, $320M) – R&D services in synthetic and medicinal chemistry, biology, DMPK, pharmacology and toxicology for Biopharma industry. Backed by CITIC M&A Fund, Legend Capital, Aisling Capital and DCM Ventures.
Precision for Medicine (2011, Checy Chase, $225M) – Integrated infrastructure and services for biopharma drug development for the era of precision medicine. Backed by TPG Capital, Oak Investment Partners, J.H. Whitney & Co and others. 
JHL Biotech (2012, Hsinchu, $81M) – Contract research and manufacturing solutions for biologic medicines in Asia. Backed by Milestone Capital, Milestone Capital China, Liwick Investment Management, Sungent BioVenture.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates visit Biotech and Pharma feeds.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – FITNESS AND WELLNESS

• OMsignal, a developer of smart apparel that can monitor heart rate and activity, raised $10M in a Series B funding round led by Relay Ventures. Link
• Happify, an online platform to improve mental and emotional health through gamification, raised $5M in a Series B funding round. Link
• Awarables, a developer of wearable that identifies and treats sleep disorders, raised $500k in a Seed funding round from Baltimore based Abell Foundation. Link
• Cult Fitness, a fitness center offering machine-free training regime, have its controlling stakes acquired by CureFit for $3M. Link
• Fitbit, a fitness wearable company, launches 2 new products – Charge 2 and Flex 2. Link
• Samsung launches Gear Fit 2 and Gear IconX fitness wearables. Link
• TomTom announced three new fitness tracking wearables. Link
• Fitbit opens office in Ireland to serve as Europe, Middle East and Africa headquarters. Link

SOME INTERESTING STARTUPS FOUND

Updown Fitness (2015, Madison) – Updown Fitness is a mobile app for personalized fitness workouts. The workout is dynamically generated to meet the user’s goals. Updown learns from the user’s progress and adjusts routines accordingly. The application encourages engagement in activity and exercise through point-based incentives.

LEADER BOARD – FITNESS AND WELLNESS

Physical Health – Monitoring – Wearables
Fitbit (2007, SF, IPO) – Wireless wearable fitness tracker to track a person’s daily activities. Went public in 2015.
Jawbone (1999, SF, $1B) – Fitness wristband with algorithm for tracking daily activities. Backed by KPCB, Andreessen Horowitz, Khosla Ventures, Sequoia Capital and more.
Misfit (2011, Redwood City, $63M, Acq.) – Develops wearable products to track daily activities. Backed by GGV Capital, Founders Fund, Khosla Ventures and more. Acquired by Fossil in 2015.

Physical Health – Monitoring – Devices
Peloton Cycle (2012, NYC, $119M) – Cloud-based live streaming of instructional cycling exercise content with social elements. Backed by Tiger Global, True Ventures and Grace Beauty Capital.

Physical Health – Monitoring – Apps
MapMyFitness (2007, Austin, $24M, Acq.) – App-based tracking of workouts like running, cycling, walking etc. Backed by Austin Ventures and Milestone Venture Partners. Acquired by UnderArmour in 2013.
MyFitnessPal (2005, SF, $18M, Acq.) – Mobile app to track calorie intake & exercises. Backed by KPCB and Accel. Acquired by UnderArmour in 2015.

Physical Health – Delivery Channel – Offline – Fitness Centres
ClassPass (2013, NYC, $84M) – Monthly membership for fitness classes across multiple gyms and studios. Backed by General Catalysts Partners and Google Ventures.
Quancheng Relian (2014, Beijing, $17M) – Mobile app for booking gyms and fitness centers with subscription passes. Backed by Matrix Partners and Legend Capital China.

Physical Health – Delivery Channel – Offline – Coaches
Fitmob (2013, SF, $15M, Acq.) – Online marketplace for finding and booking workouts with trainers. Backed by Arena Ventures, Mayfield Fund, Marc Bell Ventures and more. Acquired by Classpass in 2015.
CoachUp (2011, Boston, $9M) – Online marketplace that connects athletes with private coaches. Backed by General Catalyst Partners, Point Judith Capital and Breakaway Innovation Group.

Physical Health – Delivery Channel – Online
Grokker (2012, San Jose, $15.5M) – Online marketplace offering video classes with the content in fitness. Backed by Khosla Ventures, Correlation Ventures, First Round Capital and Interwest Partners.
SportQ (2012, Shanghai, $10M) – App-based platform for fitness enthusiasts to consult professional coaches online. Backed by SIG China and SmallVille Capital.

Physical Health – Social Platform
Strava (2009, SF, $35M) – Online social network for users to compare and compete with each other. Backed by Sequoia Capital, Madrone Capital Partners and Sigma Partners.
JoyRun (2014, Guangzhou, $18M) – Social networking app for jogging. Backed by The Arena Capital, Innovation Works and more.

Physical Health – Tools for Fitness Centers
Netpulse (2009, SF, $52M) – Saas platform for fitness clubs. Backed by Nokia Growth Partners, Javelin Venture Partners, Draper Frontier and more.

Physical Health – Information Portal
HealthiNation (2005, NYC, $14M) – Provider of health & wellness content through videos. Backed by Intel Capital.

Physical Health – App Studio
Azumio (2011, Palo Alto, $3.4M) – Developer of mobile applications for healthcare. Backed by Founders Fund, Accel and Felicis Ventures.

Mental Health
SleepNumber (1987, Minneapolis, IPO) – Sleep monitoring through hidden sensors inside the bed. Went public in 1998.
Headspace (2010, LA, $39M) – Guided meditation sessions and mindfulness training through app/web. Backed by The Chernin Group, Advancit Capital, Allen & Company and more.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates, visit Fitness and Wellness feed.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – DIAGNOSTICS

• Color Genomics closes $45M Series B, led by General Catalyst Partners, for its direct-to-consumer genetic testing services. Link
• IDbyDNA, which is developing a metagenomic approach to infectious disease diagnosis, closes $9M Series A round. Link
• OncoDNA, specialist in pharmacogenomic solutions, raises  €7.7M equity financing round. Link
• Armune Biosciences, developer of molecular diagnostic tests for cancer, raises $5M Series A, Link
• Immortagen, which develops AI-based next-gen sequencing solutions for women’s cancer, raises Series A round. Link
• Quanterix invests in Israeli ImmunArray to boost neurodegenerative disease diagnostics efforts. Link
• DNAe wins $51.9M BARDA contract for semiconductor-based next-generation sequencing diagnostics for antimicrobial resistant infections and influenza. Link
• Danaher to acquire molecular diagnostics leader Cepheid for $4B in cash. Link
• Rennova Health acquire pharmacogenetics specialist Genomas; adds drug metabolism test PhyzioType to its portfolio. Link
• Intuitive Surgical forms $100M joint venture with Fosun Pharma in China for robot-assisted diagnosis and treatments of lung cancer. Link

SOME INTERESTING STARTUPS FOUND

BillionToOne (2015, SF) Develops tests for non-invasive prenatal testing; currently in stealth mode. Part of Y-combinator Fellowship

LEADER BOARD – DIAGNOSTICS

Oncology
Foundation Medicine (2010, Cambridge, $89.5M, Acq.) – Develops clinical assays for comprehensive genetic profiling for solid tumors and hematological malignancies to tailor personalized treatment regimens for patients. Backed by Google Ventures, KPCB, Third Rock Ventures; Roche owns a majority stake.
Biocartis (2007, Lausanne, IPO) – Develops in vitro molecular diagnostic platforms for multiplexed detection of bio-analytes in tissue samples. Backed by Debiopharm, J&J Development Corporation, Philips, The Wellcome Trust. Went public in 2015. 
NantHealth (2007, Culver City, IPO) – Combines molecular medicine and bioinformatics with technology services to enable personalized therapies for cancer and other diseases. Part of billionaire Patrick Soon-Shiong’s NantWorks system. Backed by the Kuwait government, Blackberry, Celgene, AllScripts.
Adaptive Biotechnologies (2008, Seattle, $404M) – Develops high-throughput immunosequencing technologies, first application being fordiagnosis of minimal residual disease in blood cancers. Backed by Viking Global, Illumina, Celgene, Lab Corp, Rock Spring Capital.
Guardant Health (2012, Redwood City, $190M) – Develops biopsy-free cancer detection and treatments using digital sequencing technology. Backed by Sequoia, Khosla Ventures, Orbimed, Lightspeed Venture Partners.

Cardiovascular Disease
Acutus Medical (2011, San Diego, $157M) – Develops medical imaging technologies for the electrophysiological market; first product gives an ultrasound-based reconstruction of the heart to diagnose arrhythmias. Backed by Advent Life Sciences, Orbimed, GE Ventures, Xeraya, Deerfield Capital.

Immune Disease
Exagen Diagnostics (2002, Vista, $76M) – Rheumatology specialty company that focuses on the diagnosis and prognosis of autoimmune connective tissue diseases. Backed by Epic venture capital, vSpring Capital, Sun Mountain Capital.

Infectious disease
Oxford Immunotec (2002, Abingdon, IPO) – Proprietary T-SPOT platform that measures immune cell responses at a single cell level to detect infectious diseases such as tuberculosis and CMV even at low pathogen loads. Backed by Dow, Clarus Ventures, New Leaf Venture Partners, Spark Ventures. Went public in 2013. 
Atlas Genetics (2005, Bristol UK, $76M) – Develops the microfluidic-based multiplex point-of-care system io™ to detect bacterial STDs and hospital acquired infections. Backed by J&J Development Corporation, Novartis, BB Biotech, Consort Medical, Life Science Venture Partners.

Reproductive Health
Natera (2004, Redwood City, IPO) – Specializes in pre-implantation genetic testing, conception testing and non-invasive prenatal diagnostics. Backed by Claremont Creek Ventures, Sequoia, Orbimed Advisors, Sofinnova Ventures, Lightspeed Venture Partners. Went public in 2015.
Sera Prognostics (2008, Salt Lake City, $50M) – Develops a proteomics tests for assessing risk of pre-term birth in expectant mothers. Backed by Domain Associates, Catalyst Health Ventures, Interwest and Upstart Capital.

CNS
Assurex Health (2006, Mason, $92M, Acq.) – Develops pharmacogenomics platforms for neuropsychiatric disorders. Backed by Mayo Clinic, Claremont Creek, Allos Ventures, Sequoia, GE Capital, jVen Capital.
Avid Radiopharmaceuticals (2005, Philadelphia, $70M, Acq.) – Specializes in molecular imaging agents for diagnosis of chronic diseases. Backed by Bioadvance, RK Ventures, Lilly Ventures, Safeguard Scientific, Pfizer. Acquired by Eli Lilly in 2010 for $800M.

Platform
SuperSonic Imagine (2005, Aix-en-Provence, IPO) – Develops ultrasound imaging platforms, with applications in women health, vascular, hepatology, gastroenterology and general imaging. Backed by NBGI Private Equity, Rothschild, Auriga Partners, Omnes Capital, Alto Invest. Went public in 2014.
Singulex (2003, Alamedia, $87M) – Specializes in single molecule counting technology and biomarker research for diagnostics. Backed by GE Capital, Advantage Capital, Prolog Ventures, Orbimed, Jafco.
Personalis (2011, Menlo Park, $75M) – Use proprietary databases, human reference sequences, and sophisticated algorithms to analyze genome scale information for clinical diagnostics. Backed by Mohr Davidow Ventures, Lightspeed Venture Partners, Abingworth.

Suite
23andMe (2006, Mountain View, $232M) – Provides direct-to-consumer service of gene indexing w.r.t. ancestry, genealogy, and inherited traits. Backed by J&J Development Corporation, NEA, Google Ventures, Illumina, Fidelity Investments, Mohr Davidow, MPM Capital.
SomaLogic (1999, Boulder, $169M) – Develops proteomics tools with applications in clinical diagnostics and life science research. Backed by Novartis, Gates Foundation, Visium Healthcare.
Pathway Genomics (2008, San Diego, $70M) – Develops genetic tests for cancer risk and drug responses. Backed by KCP Capital, Edelson Tech, Founders Fund, IBM.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – TELEMEDICINE

• Specialists On Call, a provider of clinical telemedicine services to acute care hospitals, raised $50M in Series G round of funding from CRG, a healthcare focussed investment firm. Link
• Curology, a telemedicine platform to consult a dermatologist, raised $15M in Series B round of funding led by Advance Vixeid Partners and joined by Sherpa Capital and Forerunner Ventures. Link
• HaloDoc, an online platform to consult with doctors through video calls, voice calls and chat, raised $13M in Series A round of funding led by Clermont Group. Link
• StatRad, which offers teleradiology service to the providers, raised $13 million equity investment from an undisclosed institutional partner. Link
• Kry, a telemedicine company that allows patients to take video consultation with the doctors, closed a Seed funding round of $7M led by Index Ventures and Creandum. Link
• Doctor Insta, a telemedicine platform for remote health consultation via video conferencing raised over $1M in Series A round of funding led by Round Glass Partners. Link
• MedWand, a telemedicine device startup, raised Series A funding round led by Maxim Ventures. Link
• Glooko, a diabetes management solution for patients, health systems, and payer groups completed a merger with Diasend and raised $8M. Link
• FasPsych, a telepsychiatry services provider, got acquired by Pharos Capital. Link
• LoveDoctor, an online platform to get chat-based consultation on sexual health and relationships anonymously, got acquired by Sheroes for an undisclosed amount. Link
• American Well moves into telepsychiatry, hires behavioral health VP. Link

SOME INTERESTING STARTUPS FOUND

Physician 360 (2015, Dallas) – Physician360 provides an in-home rapid strep and flu test, and accompanying telemedicine service powered by diagnostic algorithms and physicians. The product has accompanying software powered by diagnostic algorithms, which according to the company, in retrospective studies were more accurate in diagnosing strep throat than an actual physician.

LEADER BOARD – TELEMEDICINE

Tele-Consultation
Teladoc (2002, Dallas, IPO) – Telemedicine provider offering web and mobile based video consultation. Backed by Cardinal Partners, HLM Venture Partners, Trident Capital, New Capital Partners, Jafco Ventures, Kleiner Perkins Caufield & Byers, Greenspring Associates, BNY Mellon, Questmark Partners, FLAG Capital Management. Went public in July 2015.
Specialists On Call (2004, Reston, $182M) – Telemedicine services for Tele-Neurology, Tele-Psychiatry and Tele-Intensivist. Backed by Warburg Pincus.
American Well (2006, Boston, $123M) – Telehealth platform that connects users with doctors. Backed by Inventure Partners.
Doctor On Demand (2012, SF, $87M) – Telemedicine services based on a pay-per-use model. Backed by Venrock, Shasta Ventures, Qualcomm Ventures.
MDLIVE (2009, Sunrise, $74M) – Online and on-demand telemedicine services. Backed by Bedford Funding, Heritage Group, Sutter Health, Kanye Capital.

Tele-Monitoring
iRhythm Technologies (2006, SF, $95M) Remote cardiac rhythm monitoring device. Backed by Mohr Davidow Ventures.
Watermark Medical (2008, Boca Raton, $53M) Home sleep testing solutions to determine presence and severity of obstructive sleep apnea. Merged with SleepMed. Backed by Ballast Point Ventures.
MD Revolution (2011, San Diego, $34M) Platform for healthcare providers to predict and prevent chronic disease via behaviour change. Backed by Jump Capital.
Healthsense (2001, Mendota, $33M) Remote monitoring, emergency calls and wellness management solutions. Backed by Radius Ventures, Merck & Co., Mansa Capital, Merck Global Health Innovation Fund.

Tele-Rehabilitation
Pursuant Health (2007, Atlanta, $29M) Interactive healthcare platforms and kiosks. Backed by WellPoint, Novartis, Dell, Coinstar.

Tech Enablers
InTouch Health (2002, Santa Barbara, $64M) Proprietary communications and mobile robotic platform. Backed by Acacia VP, iRobot, Beringea.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates visit Telemedicine feed.

A daily newsletter summarizing recent activity & interesting startups globally

RECENT NOTABLE ACTIVITY – MEDICAL DEVICES

• Abbott received FDA approval for its FreeStyle Libre Pro continuous glucose monitoring system. Link
• Medtronic received FDA approval for its MiniMed 670G hybrid closed looped system. Link
• Edwards Lifesciences received CE mark approval for its Sapien 3 TAVR to cover aortic stenosis patients at intermediate risk for open-heart surgery. Link
• ViewRay received CE Mark approval for its MRIdian Linac next-gen linear accelerator-based MRI-guided radiation therapy system. Link
• Obalon Therapeutics registered for an IPO worth $75M and received PMA from the FDA for its ingestible, gas-filled weight-loss balloon. Link
• Allergan received FDA approval for its Natrelle Inspira cohesive breast implants for women undergoing breast reconstruction, augmentation or revision surgery. Link
• GI-View received FDA 510(k) clearance for its Aer-O-Scope colonoscopy device. Link
• Johnson & Johnson to acquire Abbott’s eye surgery unit for $4.33B. Link
• ConvaTec plans to raise about $1.8B in an initial public offering on the London Stock Exchange. Link
• Terumo is reportedly eyeing a $1.5B deal for Abbott‘s cardiovascular device business. Link
• Intarcia Therapeutics, a developer of drug delivery system for the treatment of type 2 diabetes, raised $215M in a funding round led by institutional investors and existing investors. Link
• Chrono Therapeutics, a developer of transdermal nicotine replacement therapy for smoking cessation, raised $48M in a Series B round led by Kaiser Permanente. Link
• T2 Biosystems, a developer of diagnostic products to improve patient health, raised $40M funding from Canon in a private placement. Link
• Spineart, a developer of orthopedic implants and instruments, raised €30M in a funding round from Gimv. Link

SOME INTERESTING STARTUPS FOUND

Theranica (2016, Netanya) – Develops chip-based wearable patch for neuromodulation therapy.
NIMD (2015, Jerusalem) – Develops noninvasive microwave heating technology for cancer treatment.

LEADER BOARD – MEDICAL DEVICES

THERAPEUTICS
Cardiovascular
TriVascular (1998, Santa Rosa, IPO) – Medical devices for endovascular aortic repair. Went public in 2014.
CVRx (2001, Minneapolis, $390M) – Implantable technology for hypertension and heart failure. Backed by DaVita Healthcare Partners, Piper Jaffray, Ysios Capital, JJDC, InterWest Partners, Silicon Valley Bank, SightLine Partners, NEA, Kearny Venture Partners, Frazier Healthcare Partners, ABS Ventures.

Orthopedics
ConforMIS (2004, Bedford, IPO) – Personalized, partial knee resurfacing implants to treat knee osteoarthritis. Went public in 2015.
Small Bone Innovations (2009, Morrisville, $171M) – Suite of orthopedic products for small bones and joints. Backed by Trevi Health Ventures, Goldman Sachs, Malaysian Life Sciences Capital Fund, NGN Capital, Viscogliosi Brothers, Axiom Ventures, Khazanah Nasional Berhad, 3i Group.

Surgery
Auris Surgical Robots (2009, San Carlos, $184M) – Robotic microsurgical systems for ophthalmic surgery. Backed by NaviMed Capital, Lux Capital, Mithril Capital Management and Highland Capital Partners.
Medrobotics (2011, Raynham, $140M) – Robotic surgical devices for minimally invasive surgery. Backed by Hercules Technology Growth Capital and Pittsburgh Life Sciences Greenhouse.

Ophthalmology
TearScience (2005, Morrisville, $151M) – Diagnosis and Treatment of Evaporative Dry Eye. Backed by Spray Venture Partners, Essex Woodlands Health Ventures, eneralcatalyst.com, HealthCare Royalty Partners, Investor Growth Capital, DeNovo Ventures and Quaker BioVentures.
Avedro (2007, Waltham, $130M) – Corneal cross-linking technology. Backed by Interwest, OrbiMed Advisors, Prism Venture Management, DeNovo Ventures, Flagship Ventures, Aperture Venture Partners, SCP Vitalife Partners, Borealis Ventures, Abingworth, Third Point, and Prism Venture.

DIAGNOSTICS
Platform Technologies
Neusoft Medical System (1998, Shenyang, $410M) – Medical imaging device and software developer. Backed by China Everbright Group AG, Goldman Sachs, Hony Capital.
Butterfly Network (2011, Guilford, $100M) – Medical imaging devices using a combination of deep learning and an ultrasonic device. Backed by Aeris Capital.

Oncology
Veran Medical (2005, St.Louis, $83M) – Soft tissue navigation for diagnosis of lung cancer. Backed by Prolog Ventures, Versant Ventures, River Cities Capital Funds, Advantage Capital Partners, Rex Health Ventures, 3G Capital Partners and Vectis.
SuperDimension (1995, Minneapolis, $63M) – Electromagnetic navigation bronchoscopy to diagnose and treat cancer. Backed by Orbimed, Pitango Venture Capital, Saints Capital, Oxford Bioscience Partners, Oxford Capital, Pfizer, Covidien, CIBC Equity Research, Medica Venture Partners and Tivona Capital.

Infectious Disease
Accelerate Diagnostics (2004, Tucson, IPO) – In vitro diagnostics to provide solutions for the antibiotic resistant infections. Went public in 2013.
Curetis (2007, Holzgerlingen, $85M) – Molecular diagnostics POC device for infectious diseases. Backed by Forbion, KfW Bankengruppe, HBM Partners, BioMedPartners, CD-Venture GmbH, Roche, Qiagen, Life Sciences Partners, Aeris Capital.

MONITORING
Diabetes
OptiScan Biomedical (1994, Hayward, $156M) – Glucose monitoring systems for ICUs/CCUs. Backed by yet2Ventures, Mitsui, Medven, Lightstone Ventures, Oakwood Medical, Ascension Ventures, NGN Capital, Signet Healthcare Partners, Mitsui, Hercules Technology Growth Capital, Prism Venture, EGS Healthcare Capital Partners, Morgenthaler.
Senseonics (1996, Germantown, $124M) – Implantable system for continuous glucose monitoring. Backed by NEA, HealthCare Ventures, Rho Capital Partners, Anthem Capital Management, Delphi Ventures and Greenspring Associates.

Cardiovascular
CardioMEMS (2001, Atlanta, $153M, Acq.) – Wireless sensor-based implants for cardiac monitoring. Acquired by St. Jude Medical in 2014.
iRhythm Technologies (2006, SF, $95M) – Cardiac rhythm monitoring devices. Backed by Mohr Davidow Ventures, Synergy Life Science Partner, Novo A/S, Norwest Venture Partners, California HealthCare Foundation, Stanford University, Kaiser Permanente Ventures, New Leaf Venture Partners and New Leaf Ventures.

Vital Signs
EarlySense (2004, Ramat Gan, $85M) – Contact free patient monitoring solution. Backed by Noaber, Bridge Investment Fund, Samsung Venture Investment Corporation, Docor, ProSeed, Pitango VC, Israel, Mitsui & Co, JK&B Capital, Bank Hapoalim, Welch Allyn, Challenge.
Sotera Wireless (2004, San Diego, $68M) – In hospital patient monitoring device. Backed by Sanderling Ventures, Qualcomm Ventures, Intel Capital, EDB Investments, Safeguard, Delphi Ventures, Cerner Capital, West Health and Sanderling.

CLINICAL EQUIPMENT
TransMedics (1998, Andover, $264M) – Organ transplantation technology. Backed by Tudor Funds, Abrams Capital, Flagship Ventures, Kleiner Perkins, Foundation Capital, Sagamore, Hercules Technology Growth Capital, Alta Partners, Sherbrooke Capital, VantagePoint Capital Partners and i Group plc.
Caesarea Medical Electronics (1993, Caesarea, $100M) – Infusion and syringe pump systems and accessories. Backed by CareFusion.

Leaderboard includes all the top funded, IPO and successfully running bootstrapped companies along with their location, founding year and funding amount.

For latest updates, visit Medical Devices feed.